Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation

Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation

<p>Abstract</p> <p>Background</p> <p>Insulin receptor substrate (IRS) proteins are key moderators of insulin action. Their specific regulation determines downstream protein-protein interactions and confers specificity on growth factor signalling. Regulatory mechanisms t...

Full description

Bibliographic Details
Main Authors:	James Stephen R, Kaiser Christina
Format:	Article
Language:	English
Published:	BMC 2004-11-01
Series:	BMC Biology
Online Access:	http://www.biomedcentral.com/1741-7007/2/23

Similar Items

Reduced Tyrosine and Serine-632 Phosphorylation of Insulin Receptor Substrate-1 in the Gastrocnemius Muscle of Obese Zucker Rat
by: Mohammad Shamsul Ola
Published: (2022-11-01)

Dihydromyricetin Attenuates Metabolic Syndrome And Improves Insulin Sensitivity By Upregulating Insulin Receptor Substrate-1 (Y612) Tyrosine Phosphorylation In db/db Mice
by: He J, et al.
Published: (2019-11-01)

Non-catalytic tyrosine-phosphorylated receptors.
by: Dushek, O, et al.
Published: (2012)

Cytochrome C is tyrosine 97 phosphorylated by neuroprotective insulin treatment.
by: Thomas H Sanderson, et al.
Published: (2013-01-01)

Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development.
by: Jensen, C, et al.
Published: (2008)

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
by: Alison L Kearney, et al.
Published: (2021-07-01)

Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice
by: Deepa Mathew, et al.
Published: (2023-08-01)

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation.
by: Bryan D Bryson, et al.
Published: (2015-01-01)

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation
by: Bryson, Bryan D., et al.
Published: (2015)

Investigating the mechanism of non-catalytic tyrosine-phosphorylated receptor triggering
by: Denham, E
Published: (2016)

Membrane lipid rafts are required for AMPA receptor tyrosine phosphorylation
by: Takashi Hayashi, et al.
Published: (2022-10-01)

Altered Insulin Receptor Substrate 1 Phosphorylation in Blood Neuron-Derived Extracellular Vesicles From Patients With Parkinson’s Disease
by: Szu-Yi Chou, et al.
Published: (2020-12-01)

Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation.
by: Koji Tsutsumi, et al.
Published: (2010-04-01)

Insulin receptor tyrosine kinase substrate enhances low levels of MDM2-mediated p53 ubiquitination.
by: Ke-Sheng Wang, et al.
Published: (2011-01-01)

Protocol to characterize extracellular c-Src tyrosine kinase function through substrate interaction and phosphorylation
by: Michael P. Omini, et al.
Published: (2023-12-01)

Metabolic signatures of regulation by phosphorylation and acetylation
by: Kirk Smith, et al.
Published: (2022-01-01)

Biphasic modulation of insulin receptor substrate-1 during goitrogenesis
by: R. Grozovsky, et al.
Published: (2007-05-01)

Fyn tyrosine kinase increases Apolipoprotein E Receptor 2 levels and phosphorylation.
by: Teal C Burrell, et al.
Published: (2014-01-01)

A systematic investigation on the mechanism of non-catalytic tyrosine phosphorylated receptor triggering
by: Denham, E, et al.
Published: (2014)

Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT)
by: Levsh, Olesya, et al.
Published: (2020)

Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT).
by: Ying-Chih Chiang, et al.
Published: (2018-10-01)

Role of receptor protein tyrosine phosphatase alpha (RPTPalpha) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels.
by: Imbrici, P, et al.
Published: (2000)

Protein Tyrosine Phosphorylation in the Ischemic Brain
by: Norio Takagi
Published: (2014-01-01)

PCAF, SIRT1 and the regulation of substrate acetylation
by: Serrano, L
Published: (2021)

Tyrosine-phosphorylated DNER sensitizes insulin signaling in hepatic gluconeogenesis by inducing proteasomal degradation of TRB3
by: Junfeng Li, et al.
Published: (2024-05-01)

Phase separation of insulin receptor substrate 1 drives the formation of insulin/IGF-1 signalosomes
by: Xiu Kui Gao, et al.
Published: (2022-06-01)

N-acetylation and phosphorylation of Sec complex subunits in the ER membrane
by: Soromani Christina, et al.
Published: (2012-12-01)

Tyrosine Phosphorylation Regulates the Activity of Phytochrome Photoreceptors
by: Kazumasa Nito, et al.
Published: (2013-06-01)

Platelet Acetyl-CoA Carboxylase Phosphorylation
by: Shakeel Kautbally, MD, et al.
Published: (2019-09-01)

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
by: Marianne R. Spalinger, et al.
Published: (2023-02-01)

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response
by: Lee, K.-G., et al.
Published: (2013)

Pyruvate Dehydrogenase A1 Phosphorylated by Insulin Associates with Pyruvate Kinase M2 and Induces LINC00273 through Histone Acetylation
by: Abu Jubayer Hossain, et al.
Published: (2022-05-01)

Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.
by: Ladan Parhamifar, et al.
Published: (2010-12-01)

Role of Receptor Protein Tyrosine Phosphatases (RPTPs) in Insulin Signaling and Secretion
by: Julio Sevillano, et al.
Published: (2021-05-01)

A novel two-ligand system for investigation of signal integration by non-catalytic tyrosine-phosphorylated receptors
by: Paterson, R
Published: (2016)

Manipulating Tyrosine Phosphorylation by Heterobifunctional Small Molecules
by: Xianke Meng, et al.
Published: (2023-08-01)

Development and Applications of Chimera Platforms for Tyrosine Phosphorylation
by: Rajaiah Pergu, et al.
Published: (2023-08-01)

Regulatory phosphorylation of Ikaros by Bruton's tyrosine kinase.
by: Hong Ma, et al.
Published: (2013-01-01)

Tyrosine phosphorylation of Grb14 by Tie2
by: Dumont Daniel J, et al.
Published: (2010-10-01)

Ligand binding affinity at the insulin receptor isoform A (IR-A) and subsequent IR-A tyrosine phosphorylation kinetics are important determinants of mitogenic biological outcomes.
by: Harinda eRajapaksha, et al.
Published: (2015-07-01)