Improving the Effect of Ferulic Acid on Inflammation and Insulin Resistance by Regulating the JNK/ERK and NF-κB Pathways in TNF-α-Treated 3T3-L1 Adipocytes

Improving the Effect of Ferulic Acid on Inflammation and Insulin Resistance by Regulating the JNK/ERK and NF-κB Pathways in TNF-α-Treated 3T3-L1 Adipocytes

In this study, ferulic acid was investigated for its potential in suppressing TNF-α-treated inflammation and insulin resistance in adipocytes. Ferulic acid suppressed TNF-α, IL-6, IL-1β, and MCP-1. TNF-α increased p-JNK and ERK1/2, but treatment with ferulic acid (1, 10, and 50 μM) decreased p-JNK a...

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Bibliographic Details
Main Authors:	Jae-Eun Park, Ji-Sook Han
Format:	Article
Language:	English
Published:	MDPI AG 2024-01-01
Series:	Nutrients
Subjects:	ferulic acid inflammation JNK/ERK MAPK NF-κB pathway
Online Access:	https://www.mdpi.com/2072-6643/16/2/294

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