Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads
Abstract $$\beta$$ β -methylamino-L-alanine (BMAA) is a neurotoxic non-protein amino acid found in the tissues of cycad plants. The demonstrated toxicity of BMAA to diverse organisms, including humans, is widely assumed to imply a defensive function of BMAA against herbivores; however, this hypothes...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-09298-3 |
| _version_ | 1819011622592577536 |
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| author | Melissa R. L. Whitaker Florence Gilliéron Christina Skirgaila Mark C. Mescher Consuelo M. De Moraes |
| author_facet | Melissa R. L. Whitaker Florence Gilliéron Christina Skirgaila Mark C. Mescher Consuelo M. De Moraes |
| author_sort | Melissa R. L. Whitaker |
| collection | DOAJ |
| description | Abstract $$\beta$$ β -methylamino-L-alanine (BMAA) is a neurotoxic non-protein amino acid found in the tissues of cycad plants. The demonstrated toxicity of BMAA to diverse organisms, including humans, is widely assumed to imply a defensive function of BMAA against herbivores; however, this hypothesis has not previously been tested in an ecologically relevant system. We investigated the effects of dietary BMAA, across a range of dosages matching and exceeding levels typically present in cycad leaves, on the feeding preferences and performance of a generalist lepidopteran herbivore (Spodoptera littoralis).We observed no effects of dietary BMAA on the survival or development of S. littoralis larvae, nor any larval preference between BMAA-laced and control diets. These findings suggest that BMAA in cycad tissues does not deter feeding by insect herbivores, raising questions about other potential physiological or ecological functions of this compound. |
| first_indexed | 2024-12-21T01:31:05Z |
| format | Article |
| id | doaj.art-fce5f98c46854ea09d66ac7fe7a92802 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-21T01:31:05Z |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-fce5f98c46854ea09d66ac7fe7a928022022-12-21T19:20:22ZengNature PortfolioScientific Reports2045-23222022-04-011211610.1038/s41598-022-09298-3Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycadsMelissa R. L. Whitaker0Florence Gilliéron1Christina Skirgaila2Mark C. Mescher3Consuelo M. De Moraes4Department of Environmental Systems Science, ETH ZürichDepartment of Environmental Systems Science, ETH ZürichDepartment of Environmental Systems Science, ETH ZürichDepartment of Environmental Systems Science, ETH ZürichDepartment of Environmental Systems Science, ETH ZürichAbstract $$\beta$$ β -methylamino-L-alanine (BMAA) is a neurotoxic non-protein amino acid found in the tissues of cycad plants. The demonstrated toxicity of BMAA to diverse organisms, including humans, is widely assumed to imply a defensive function of BMAA against herbivores; however, this hypothesis has not previously been tested in an ecologically relevant system. We investigated the effects of dietary BMAA, across a range of dosages matching and exceeding levels typically present in cycad leaves, on the feeding preferences and performance of a generalist lepidopteran herbivore (Spodoptera littoralis).We observed no effects of dietary BMAA on the survival or development of S. littoralis larvae, nor any larval preference between BMAA-laced and control diets. These findings suggest that BMAA in cycad tissues does not deter feeding by insect herbivores, raising questions about other potential physiological or ecological functions of this compound.https://doi.org/10.1038/s41598-022-09298-3 |
| spellingShingle | Melissa R. L. Whitaker Florence Gilliéron Christina Skirgaila Mark C. Mescher Consuelo M. De Moraes Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads Scientific Reports |
| title | Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads |
| title_full | Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads |
| title_fullStr | Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads |
| title_full_unstemmed | Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads |
| title_short | Experimental evidence challenges the presumed defensive function of a “slow toxin” in cycads |
| title_sort | experimental evidence challenges the presumed defensive function of a slow toxin in cycads |
| url | https://doi.org/10.1038/s41598-022-09298-3 |
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