PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS
ABSTRACT Objective: This study was carried out to find diagnostic accuracy of platelet count to spleen diameter ratio as a predictor of esophageal varices in patients of liver cirrhosis due to Hepatitis C virus taking upper gastrointestinal tract endoscopy as gold standard. Design: Cross-sectional s...
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| Format: | Article |
| Language: | English |
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University of Faisalabad
2012-06-01
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| Series: | Journal of University Medical & Dental College |
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| Online Access: | http://jumdc.com/index.php/jumdc/article/view/340 |
| _version_ | 1811285468087582720 |
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| author | Khalid Amin Dilshad Muhammad |
| author_facet | Khalid Amin Dilshad Muhammad |
| author_sort | Khalid Amin |
| collection | DOAJ |
| description | ABSTRACT Objective: This study was carried out to find diagnostic accuracy of platelet count to spleen diameter ratio as a predictor of esophageal varices in patients of liver cirrhosis due to Hepatitis C virus taking upper gastrointestinal tract endoscopy as gold standard. Design: Cross-sectional study. Setting: DHQ Hospital, Faisalabad. Duration of study: Six (6) months from staring from April 01, 2009 to September 30, 2009. Subjects and methods: 95 patients of either sex having cirrhosis of liver secondary to Hepatitis C virus (diagnosed by coarse echo texture with reduced liver span on abdominal ultrasonography and positive polymerase chain reaction for Hepatitis C virus were considered as cirrhotic) were included in the study. All relevant investigations were carried out including upper gastrointestinal tract endoscopy, abdominal ultrasound scan, complete blood count, serum albumin level, serum billirubin level, prothrombin time (PT) and other clinical sign were recorded. Results: Forty seven (49.5%) patients were male and 48 (50.5%) patients were females. Mean platelet count was 133.22+22.83×103/mm3 of patients who have not developed varices yet and mean platelet count was 97.29+13.47×103/mm3 of patients who developed varices. Patients with varices had mean spleen diameter of 13.941±1.33 (centimeters) cms and without varices had 11.70±1.23 cms mean spleen diameter. The mean platelet count to spleen diameter ratio of patients without varices was 1162.41±242.43 and that of with varices was 704.28±142.11. Conclusion: Platelet count to spleen diameter ratio (considering >909 as normal) has good diagnostic accuracy in identifying cases with esophageal varices. |
| first_indexed | 2024-04-13T02:44:33Z |
| format | Article |
| id | doaj.art-fce763eddede4590b1daae6db3500b90 |
| institution | Directory Open Access Journal |
| issn | 2221-7827 2310-5542 |
| language | English |
| last_indexed | 2024-04-13T02:44:33Z |
| publishDate | 2012-06-01 |
| publisher | University of Faisalabad |
| record_format | Article |
| series | Journal of University Medical & Dental College |
| spelling | doaj.art-fce763eddede4590b1daae6db3500b902022-12-22T03:06:05ZengUniversity of FaisalabadJournal of University Medical & Dental College2221-78272310-55422012-06-0131PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUSKhalid Amin0 Dilshad Muhammad1Associate Professor of Medicine, Punjab Medical College, FaisalabadSenior Registrar, DHQ Hospital, FaisalabadABSTRACT Objective: This study was carried out to find diagnostic accuracy of platelet count to spleen diameter ratio as a predictor of esophageal varices in patients of liver cirrhosis due to Hepatitis C virus taking upper gastrointestinal tract endoscopy as gold standard. Design: Cross-sectional study. Setting: DHQ Hospital, Faisalabad. Duration of study: Six (6) months from staring from April 01, 2009 to September 30, 2009. Subjects and methods: 95 patients of either sex having cirrhosis of liver secondary to Hepatitis C virus (diagnosed by coarse echo texture with reduced liver span on abdominal ultrasonography and positive polymerase chain reaction for Hepatitis C virus were considered as cirrhotic) were included in the study. All relevant investigations were carried out including upper gastrointestinal tract endoscopy, abdominal ultrasound scan, complete blood count, serum albumin level, serum billirubin level, prothrombin time (PT) and other clinical sign were recorded. Results: Forty seven (49.5%) patients were male and 48 (50.5%) patients were females. Mean platelet count was 133.22+22.83×103/mm3 of patients who have not developed varices yet and mean platelet count was 97.29+13.47×103/mm3 of patients who developed varices. Patients with varices had mean spleen diameter of 13.941±1.33 (centimeters) cms and without varices had 11.70±1.23 cms mean spleen diameter. The mean platelet count to spleen diameter ratio of patients without varices was 1162.41±242.43 and that of with varices was 704.28±142.11. Conclusion: Platelet count to spleen diameter ratio (considering >909 as normal) has good diagnostic accuracy in identifying cases with esophageal varices.http://jumdc.com/index.php/jumdc/article/view/340Platelet count, spleen diameteresophageal varicesplatelet count to spleen diameter ratiodiagnostic accuracy |
| spellingShingle | Khalid Amin Dilshad Muhammad PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS Journal of University Medical & Dental College Platelet count, spleen diameter esophageal varices platelet count to spleen diameter ratio diagnostic accuracy |
| title | PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS |
| title_full | PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS |
| title_fullStr | PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS |
| title_full_unstemmed | PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS |
| title_short | PLATELET COUNT TO SPLEEN DIAMETER RATIO AS A PREDICTOR OF ESOPHAGEAL VARICES IN PATIENTS OF LIVER CIRRHOSIS DUE TO HEPATITIS C VIRUS |
| title_sort | platelet count to spleen diameter ratio as a predictor of esophageal varices in patients of liver cirrhosis due to hepatitis c virus |
| topic | Platelet count, spleen diameter esophageal varices platelet count to spleen diameter ratio diagnostic accuracy |
| url | http://jumdc.com/index.php/jumdc/article/view/340 |
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