Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
Clinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Kar...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Genética
2004-01-01
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| Series: | Genetics and Molecular Biology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002 |
| _version_ | 1818585592285364224 |
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| author | Rita C. V. Carrara Rui Yamasaki Luís F. Mazucatto Maria A. Llorach Veludo Edi L. Sartorato João M. Pina-Neto |
| author_facet | Rita C. V. Carrara Rui Yamasaki Luís F. Mazucatto Maria A. Llorach Veludo Edi L. Sartorato João M. Pina-Neto |
| author_sort | Rita C. V. Carrara |
| collection | DOAJ |
| description | Clinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p). |
| first_indexed | 2024-12-16T08:39:31Z |
| format | Article |
| id | doaj.art-fcee6c5b65114da59e8b9bc22f974d92 |
| institution | Directory Open Access Journal |
| issn | 1415-4757 1678-4685 |
| language | English |
| last_indexed | 2024-12-16T08:39:31Z |
| publishDate | 2004-01-01 |
| publisher | Sociedade Brasileira de Genética |
| record_format | Article |
| series | Genetics and Molecular Biology |
| spelling | doaj.art-fcee6c5b65114da59e8b9bc22f974d922022-12-21T22:37:43ZengSociedade Brasileira de GenéticaGenetics and Molecular Biology1415-47571678-46852004-01-0127447748210.1590/S1415-47572004000400002Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile menRita C. V. CarraraRui YamasakiLuís F. MazucattoMaria A. Llorach VeludoEdi L. SartoratoJoão M. Pina-NetoClinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002male infertilitycytogeneticsmicrodeletionsAZFmeiotic anomalies |
| spellingShingle | Rita C. V. Carrara Rui Yamasaki Luís F. Mazucatto Maria A. Llorach Veludo Edi L. Sartorato João M. Pina-Neto Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men Genetics and Molecular Biology male infertility cytogenetics microdeletions AZF meiotic anomalies |
| title | Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
| title_full | Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
| title_fullStr | Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
| title_full_unstemmed | Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
| title_short | Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
| title_sort | somatic and germ cell cytogenetic studies and azf microdeletion screening in infertile men |
| topic | male infertility cytogenetics microdeletions AZF meiotic anomalies |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002 |
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