Association of urinary incontinence and depression or anxiety: a meta-analysis

Objective We explored the relationship between urinary incontinence (UI) and depression or anxiety. Methods We searched the Cochrane Library, Embase, and PubMed for articles on the association between depression, anxiety, and UI. We calculated pooled 95% confidence intervals (CIs) and odds ratios (O...

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Bibliographic Details
Main Authors: Shulin Cheng, Dong Lin, Tinghui Hu, Liang Cao, Hai Liao, Xiaoxi Mou, Qiang Zhang, Junbo Liu, Tao Wu
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520931348
Description
Summary:Objective We explored the relationship between urinary incontinence (UI) and depression or anxiety. Methods We searched the Cochrane Library, Embase, and PubMed for articles on the association between depression, anxiety, and UI. We calculated pooled 95% confidence intervals (CIs) and odds ratios (ORs). Results Twelve articles (31,462 participants) were included. The UI group had significantly higher depression and anxiety levels than the non-UI group (OR = 1.73, 95%CI: 1.64–1.82, I 2  = 75.5%). In subgroup analysis, depression and anxiety were significantly higher in participants with UI than in those without UI (OR = 1.95, 95%CI: 1.82–2.10, I 2  = 64.3% and OR = 1.54, 95%CI: 1.43–1.65, I 2  = 59.2%, respectively).  In subgroup analysis by age, participants with UI had significantly higher depression and anxiety, regardless of age, than the non-UI group (OR = 1.59, 95%CI: 1.29–1.95, I 2  = 59.1% and OR = 1.98, 95%CI: 1.62–2.43, I 2  = 75.5%, respectively). Conclusion Patients with UI had significantly higher depression and anxiety levels than those without UI. Depression and anxiety were higher in patients with UI than in those without UI, regardless of age. Larger sample sizes and more high-quality studies are needed to validate our findings.
ISSN:1473-2300