The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam
Abstract Background Taenia solium cysticercosis, recognized as a neglected tropical disease by the WHO, is distributed mostly in developing countries of Latin America, sub-Saharan Africa and Asia. Pigs and humans act as intermediate hosts, acquiring T. solium cysticerci (larval stage) in their tissu...
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| Format: | Article |
| Language: | English |
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BMC
2018-06-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13071-018-2945-y |
| _version_ | 1818264492424822784 |
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| author | Dinh Ng-Nguyen John Noh Kathleen Breen Mark Anthony Stevenson Sukwan Handali Rebecca Justine Traub |
| author_facet | Dinh Ng-Nguyen John Noh Kathleen Breen Mark Anthony Stevenson Sukwan Handali Rebecca Justine Traub |
| author_sort | Dinh Ng-Nguyen |
| collection | DOAJ |
| description | Abstract Background Taenia solium cysticercosis, recognized as a neglected tropical disease by the WHO, is distributed mostly in developing countries of Latin America, sub-Saharan Africa and Asia. Pigs and humans act as intermediate hosts, acquiring T. solium cysticerci (larval stage) in their tissue, through the ingestion of T. solium eggs shed in the faeces of humans infected with adult tapeworms. The disease has a negative impact on rural economies due to losses in productivity arising from human disease, pork carcass condemnations and loss of market access. The aim of this study was to estimate the prevalence of T. solium cysticercosis in pigs in Dak Lak Province in the Central Highlands of Vietnam and to identify household level characteristics associated with T. solium porcine cysticercosis. Methods This was a cross-sectional study of household pigs in three districts of Dak Lak Province. A total of 408 households in six villages in three districts were visited between June and October 2015. A questionnaire was administered to the head of each household, and within each household, serum samples were collected from three pigs. Serum samples were analyzed using the recombinant T24H antigen in enzyme-linked immunoelectrotransfer blot assay and lentil lectin purified glycoprotein in EITB assay. A Bayesian, mixed-effects logistic regression model was developed to identify management factors associated with the probability of a household having at least one cysticercosis-positive pig. Results The prevalence of porcine T. solium cysticercosis in this study was low at 0.94 [95% confidence interval (CI) 0.51–1.68] cases per 100 pigs at risk, in agreement with other studies conducted throughout Vietnam. Scavenging of food and coprophagy were associated with T. solium cysticercosis [odds ratios 1.98 (95% CrI: 0.55–4.74) and 2.57 (95% CrI: 1.22–4.66), respectively]. Conclusions This study proves that the seroprevalence of porcine cysticercosis in Dak Lak Province was as low as that of other studies conducted throughout Vietnam. Scavenging of food and coprophagy are modifiable factors, providing the opportunity to decrease the prevalence of porcine cysticercosis further in the province. |
| first_indexed | 2024-12-12T19:35:46Z |
| format | Article |
| id | doaj.art-fcf2c7050763498e94c968089ffff931 |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-12-12T19:35:46Z |
| publishDate | 2018-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-fcf2c7050763498e94c968089ffff9312022-12-22T00:14:19ZengBMCParasites & Vectors1756-33052018-06-011111810.1186/s13071-018-2945-yThe epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in VietnamDinh Ng-Nguyen0John Noh1Kathleen Breen2Mark Anthony Stevenson3Sukwan Handali4Rebecca Justine Traub5Faculty of Veterinary and Agricultural Sciences, University of MelbourneDivision of Parasitic Diseases and Malaria, Centers for Disease Control and PreventionDepartment of Livestock, Montana Veterinary Diagnostic LabFaculty of Veterinary and Agricultural Sciences, University of MelbourneDivision of Parasitic Diseases and Malaria, Centers for Disease Control and PreventionFaculty of Veterinary and Agricultural Sciences, University of MelbourneAbstract Background Taenia solium cysticercosis, recognized as a neglected tropical disease by the WHO, is distributed mostly in developing countries of Latin America, sub-Saharan Africa and Asia. Pigs and humans act as intermediate hosts, acquiring T. solium cysticerci (larval stage) in their tissue, through the ingestion of T. solium eggs shed in the faeces of humans infected with adult tapeworms. The disease has a negative impact on rural economies due to losses in productivity arising from human disease, pork carcass condemnations and loss of market access. The aim of this study was to estimate the prevalence of T. solium cysticercosis in pigs in Dak Lak Province in the Central Highlands of Vietnam and to identify household level characteristics associated with T. solium porcine cysticercosis. Methods This was a cross-sectional study of household pigs in three districts of Dak Lak Province. A total of 408 households in six villages in three districts were visited between June and October 2015. A questionnaire was administered to the head of each household, and within each household, serum samples were collected from three pigs. Serum samples were analyzed using the recombinant T24H antigen in enzyme-linked immunoelectrotransfer blot assay and lentil lectin purified glycoprotein in EITB assay. A Bayesian, mixed-effects logistic regression model was developed to identify management factors associated with the probability of a household having at least one cysticercosis-positive pig. Results The prevalence of porcine T. solium cysticercosis in this study was low at 0.94 [95% confidence interval (CI) 0.51–1.68] cases per 100 pigs at risk, in agreement with other studies conducted throughout Vietnam. Scavenging of food and coprophagy were associated with T. solium cysticercosis [odds ratios 1.98 (95% CrI: 0.55–4.74) and 2.57 (95% CrI: 1.22–4.66), respectively]. Conclusions This study proves that the seroprevalence of porcine cysticercosis in Dak Lak Province was as low as that of other studies conducted throughout Vietnam. Scavenging of food and coprophagy are modifiable factors, providing the opportunity to decrease the prevalence of porcine cysticercosis further in the province.http://link.springer.com/article/10.1186/s13071-018-2945-yTaenia soliumPorcine cysticercosisEpidemiologyVietnam |
| spellingShingle | Dinh Ng-Nguyen John Noh Kathleen Breen Mark Anthony Stevenson Sukwan Handali Rebecca Justine Traub The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam Parasites & Vectors Taenia solium Porcine cysticercosis Epidemiology Vietnam |
| title | The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam |
| title_full | The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam |
| title_fullStr | The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam |
| title_full_unstemmed | The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam |
| title_short | The epidemiology of porcine Taenia solium cysticercosis in communities of the Central Highlands in Vietnam |
| title_sort | epidemiology of porcine taenia solium cysticercosis in communities of the central highlands in vietnam |
| topic | Taenia solium Porcine cysticercosis Epidemiology Vietnam |
| url | http://link.springer.com/article/10.1186/s13071-018-2945-y |
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