Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility

Integrating automated liquid handling in the separation workflow of extracellular vesicles enhances specificity and reproducibility

Abstract Background Extracellular vesicles (EV) are extensively studied in human body fluids as potential biomarkers for numerous diseases. Major impediments of EV-based biomarker discovery include the specificity and reproducibility of EV sample preparation as well as intensive manual labor. We pre...

Full description

Bibliographic Details
Main Authors: Sofie Van Dorpe, Lien Lippens, Robin Boiy, Cláudio Pinheiro, Glenn Vergauwen, Pekka Rappu, Ilkka Miinalainen, Philippe Tummers, Hannelore Denys, Olivier De Wever, An Hendrix
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Nanobiotechnology
Subjects:
Extracellular vesicles
Separation
Density gradient centrifugation
Blood
Urine
Automation
Online Access:https://doi.org/10.1186/s12951-023-01917-z

Internet

https://doi.org/10.1186/s12951-023-01917-z

Similar Items