POLYMORPHISMS OF EXTRACELLULAR CONNECTIVE TISSUE REMODELING PROTEINASES AND MMP2, MMP3, MMP9 GENES, AND NEOANGIGENESIS VEGF GENE IN RETINAL MICROANGIOPATHY IN THE PATIENTS WITH TYPE 2 DIABETES MELLITUS

POLYMORPHISMS OF EXTRACELLULAR CONNECTIVE TISSUE REMODELING PROTEINASES AND MMP2, MMP3, MMP9 GENES, AND NEOANGIGENESIS VEGF GENE IN RETINAL MICROANGIOPATHY IN THE PATIENTS WITH TYPE 2 DIABETES MELLITUS

The aim of our study was to perform an association analysis between MMP2, MMP3, MMP9, VEGF gene polymorphisms and development  of non-proliferative  diabetic retinopathy (DR) in the type 2 diabetic patients (DM). Materials and methods: 201 DM patients:  90 cases of DR and 111  subjects  without DR f...

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Main Authors: Alla Vladimirovna Shevchenko, Viktor Fedorovich Prokof`ev, Vladimir Iosifovich Konenkov, Vadim Klimontov, Nadezhda Viktorovna Tyan, Dmitriy Chernykh, Aleksandr Trunov, Valeriy Chernykh
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2019-03-01
Series:Медицинская иммунология
Subjects:
diabetic retinopathy
matrix metalloproteinases genes
vascular endothelial growth factor gene
genic networks
mathematical modelling
Online Access:https://www.mimmun.ru/mimmun/article/view/1603

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