RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM
<p>The multi species oral bacterial biofilm contributes to plaque formation, tooth caries, infection of oral mucosa and also periodontal disease. Caries prevention is possible by controlling the bacterial population, eg by application of antibiotics. The use of antibiotics in this way is not c...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Faculty of Dentistry, Universitas Indonesia
2015-09-01
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| Series: | Journal of Dentistry Indonesia |
| Subjects: | |
| Online Access: | http://jdentistry.ui.ac.id/index.php/JDI/article/view/641 |
| _version_ | 1811251636521140224 |
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| author | Yani Corvianindya Sunarso Brotosoetarno |
| author_facet | Yani Corvianindya Sunarso Brotosoetarno |
| author_sort | Yani Corvianindya |
| collection | DOAJ |
| description | <p>The multi species oral bacterial biofilm contributes to plaque formation, tooth caries, infection of oral mucosa and also periodontal disease. Caries prevention is possible by controlling the bacterial population, eg by application of antibiotics. The use of antibiotics in this way is not curative but still effective on topical application. Betalactam antibiotics are drugs of choice because most oral infections are caused by mixture of anaerobic bacteria. The peptidoglican reaction in bacterial cell walls by betalactam results in bacterial lysis. Recently, bacterial resistance to betalactam antibiotics has been found to occur frequently by several cellular mechanisms, such as bacterial production of β-lactamase, mutation of penicillin-binding protein (PBP) with low affinity to antibiotics, or decrease of cell wall permeability to betalactam. Bacteria can acquire resistance genes by mutation or exchange of genes.</p> |
| first_indexed | 2024-04-12T16:23:23Z |
| format | Article |
| id | doaj.art-fcfa4a45881d44ada18307a43870bfa5 |
| institution | Directory Open Access Journal |
| issn | 1693-9697 2355-4800 |
| language | English |
| last_indexed | 2024-04-12T16:23:23Z |
| publishDate | 2015-09-01 |
| publisher | Faculty of Dentistry, Universitas Indonesia |
| record_format | Article |
| series | Journal of Dentistry Indonesia |
| spelling | doaj.art-fcfa4a45881d44ada18307a43870bfa52022-12-22T03:25:29ZengFaculty of Dentistry, Universitas IndonesiaJournal of Dentistry Indonesia1693-96972355-48002015-09-01112838710.14693/jdi.v11i2.641538RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAMYani Corvianindya0Sunarso Brotosoetarno1Department of Oral Biology, Faculty of Dentistry, Universitas JemberDepartment of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430<p>The multi species oral bacterial biofilm contributes to plaque formation, tooth caries, infection of oral mucosa and also periodontal disease. Caries prevention is possible by controlling the bacterial population, eg by application of antibiotics. The use of antibiotics in this way is not curative but still effective on topical application. Betalactam antibiotics are drugs of choice because most oral infections are caused by mixture of anaerobic bacteria. The peptidoglican reaction in bacterial cell walls by betalactam results in bacterial lysis. Recently, bacterial resistance to betalactam antibiotics has been found to occur frequently by several cellular mechanisms, such as bacterial production of β-lactamase, mutation of penicillin-binding protein (PBP) with low affinity to antibiotics, or decrease of cell wall permeability to betalactam. Bacteria can acquire resistance genes by mutation or exchange of genes.</p>http://jdentistry.ui.ac.id/index.php/JDI/article/view/641Bacterial population controleantibiotics applicationdrugs of choice |
| spellingShingle | Yani Corvianindya Sunarso Brotosoetarno RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM Journal of Dentistry Indonesia Bacterial population controle antibiotics application drugs of choice |
| title | RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM |
| title_full | RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM |
| title_fullStr | RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM |
| title_full_unstemmed | RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM |
| title_short | RESISTENSI BAKTERI ORAL BIOFILM TERHADAP ANTIBIOTIKA GOLONGAN BETA-LAKTAM |
| title_sort | resistensi bakteri oral biofilm terhadap antibiotika golongan beta laktam |
| topic | Bacterial population controle antibiotics application drugs of choice |
| url | http://jdentistry.ui.ac.id/index.php/JDI/article/view/641 |
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