Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine‐Cysteine Interaction

Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine‐Cysteine Interaction

Abstract Tau protein is a natively unfolded protein whose primary role is to participate in axonal transport closely associated with microtubules. Neurodegenerative disorders including Alzheimer's disease and Tauopathies involved tau protein that is found hyperphosphorylated in vivo; then, tau...

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Bibliographic Details
Main Authors: Dr. Carlos Areche, Francisca Zapata, Mathias González, Esteban Díaz, Rubén Montecinos, Marcos Hernández, Dr. Francisco Melo, Dr. Alberto Cornejo
Format: Article
Language:English
Published: Wiley-VCH 2019-05-01
Series:ChemistryOpen
Subjects:
tau protein
aggregation
fluorescence
inhibitors
medicinal chemistry
Online Access:https://doi.org/10.1002/open.201800222

Internet

https://doi.org/10.1002/open.201800222

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