Revascularization Strategy in Myocardial Infarction with Multivessel Disease
The proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock, the prognostic benefit of complete revascu...
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MDPI AG
2024-03-01
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Series: | Journal of Clinical Medicine |
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Online Access: | https://www.mdpi.com/2077-0383/13/7/1918 |
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author | Alexander Jobs Steffen Desch Anne Freund Hans-Josef Feistritzer Holger Thiele |
author_facet | Alexander Jobs Steffen Desch Anne Freund Hans-Josef Feistritzer Holger Thiele |
author_sort | Alexander Jobs |
collection | DOAJ |
description | The proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock, the prognostic benefit of complete revascularization has been demonstrated by several randomized trials and meta-analyses, leading to a strong guideline recommendation. However, similar data are lacking for ACS without ST-segment elevation (NSTE-ACS). Non-randomized data suggesting a benefit from complete revascularization in non-ST-segment elevation myocardial infarction (NSTEMI) are prone to selection bias and should be interpreted with caution. A series of large randomized controlled trials have been initiated recently to address these open questions. |
first_indexed | 2024-04-24T10:42:52Z |
format | Article |
id | doaj.art-fd018555dcd94b0db88eb120b420effa |
institution | Directory Open Access Journal |
issn | 2077-0383 |
language | English |
last_indexed | 2024-04-24T10:42:52Z |
publishDate | 2024-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Clinical Medicine |
spelling | doaj.art-fd018555dcd94b0db88eb120b420effa2024-04-12T13:21:01ZengMDPI AGJournal of Clinical Medicine2077-03832024-03-01137191810.3390/jcm13071918Revascularization Strategy in Myocardial Infarction with Multivessel DiseaseAlexander Jobs0Steffen Desch1Anne Freund2Hans-Josef Feistritzer3Holger Thiele4Department of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyThe proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock, the prognostic benefit of complete revascularization has been demonstrated by several randomized trials and meta-analyses, leading to a strong guideline recommendation. However, similar data are lacking for ACS without ST-segment elevation (NSTE-ACS). Non-randomized data suggesting a benefit from complete revascularization in non-ST-segment elevation myocardial infarction (NSTEMI) are prone to selection bias and should be interpreted with caution. A series of large randomized controlled trials have been initiated recently to address these open questions.https://www.mdpi.com/2077-0383/13/7/1918acute coronary syndromeSTEMINSTEMIrevascularizationmultivessel disease |
spellingShingle | Alexander Jobs Steffen Desch Anne Freund Hans-Josef Feistritzer Holger Thiele Revascularization Strategy in Myocardial Infarction with Multivessel Disease Journal of Clinical Medicine acute coronary syndrome STEMI NSTEMI revascularization multivessel disease |
title | Revascularization Strategy in Myocardial Infarction with Multivessel Disease |
title_full | Revascularization Strategy in Myocardial Infarction with Multivessel Disease |
title_fullStr | Revascularization Strategy in Myocardial Infarction with Multivessel Disease |
title_full_unstemmed | Revascularization Strategy in Myocardial Infarction with Multivessel Disease |
title_short | Revascularization Strategy in Myocardial Infarction with Multivessel Disease |
title_sort | revascularization strategy in myocardial infarction with multivessel disease |
topic | acute coronary syndrome STEMI NSTEMI revascularization multivessel disease |
url | https://www.mdpi.com/2077-0383/13/7/1918 |
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