Revascularization Strategy in Myocardial Infarction with Multivessel Disease

The proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock, the prognostic benefit of complete revascu...

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Main Authors: Alexander Jobs, Steffen Desch, Anne Freund, Hans-Josef Feistritzer, Holger Thiele
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/13/7/1918
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author Alexander Jobs
Steffen Desch
Anne Freund
Hans-Josef Feistritzer
Holger Thiele
author_facet Alexander Jobs
Steffen Desch
Anne Freund
Hans-Josef Feistritzer
Holger Thiele
author_sort Alexander Jobs
collection DOAJ
description The proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock, the prognostic benefit of complete revascularization has been demonstrated by several randomized trials and meta-analyses, leading to a strong guideline recommendation. However, similar data are lacking for ACS without ST-segment elevation (NSTE-ACS). Non-randomized data suggesting a benefit from complete revascularization in non-ST-segment elevation myocardial infarction (NSTEMI) are prone to selection bias and should be interpreted with caution. A series of large randomized controlled trials have been initiated recently to address these open questions.
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spelling doaj.art-fd018555dcd94b0db88eb120b420effa2024-04-12T13:21:01ZengMDPI AGJournal of Clinical Medicine2077-03832024-03-01137191810.3390/jcm13071918Revascularization Strategy in Myocardial Infarction with Multivessel DiseaseAlexander Jobs0Steffen Desch1Anne Freund2Hans-Josef Feistritzer3Holger Thiele4Department of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyDepartment of Internal Medicine/Cardiology and Leipzig Heart Institute, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, Russenstraße 69a, 04289 Leipzig, GermanyThe proportion of patients with multivessel coronary artery disease in individuals experiencing acute coronary syndrome (ACS) varies based on age and ACS subtype. In patients with ST-segment elevation myocardial infarction (STEMI) without cardiogenic shock, the prognostic benefit of complete revascularization has been demonstrated by several randomized trials and meta-analyses, leading to a strong guideline recommendation. However, similar data are lacking for ACS without ST-segment elevation (NSTE-ACS). Non-randomized data suggesting a benefit from complete revascularization in non-ST-segment elevation myocardial infarction (NSTEMI) are prone to selection bias and should be interpreted with caution. A series of large randomized controlled trials have been initiated recently to address these open questions.https://www.mdpi.com/2077-0383/13/7/1918acute coronary syndromeSTEMINSTEMIrevascularizationmultivessel disease
spellingShingle Alexander Jobs
Steffen Desch
Anne Freund
Hans-Josef Feistritzer
Holger Thiele
Revascularization Strategy in Myocardial Infarction with Multivessel Disease
Journal of Clinical Medicine
acute coronary syndrome
STEMI
NSTEMI
revascularization
multivessel disease
title Revascularization Strategy in Myocardial Infarction with Multivessel Disease
title_full Revascularization Strategy in Myocardial Infarction with Multivessel Disease
title_fullStr Revascularization Strategy in Myocardial Infarction with Multivessel Disease
title_full_unstemmed Revascularization Strategy in Myocardial Infarction with Multivessel Disease
title_short Revascularization Strategy in Myocardial Infarction with Multivessel Disease
title_sort revascularization strategy in myocardial infarction with multivessel disease
topic acute coronary syndrome
STEMI
NSTEMI
revascularization
multivessel disease
url https://www.mdpi.com/2077-0383/13/7/1918
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