Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review

Background: This review aimed to identify antimicrobial agents incorporated into dental materials obtained through additive manufacturing and their efficacy. Methods: Protocol registration was performed in Open Science Framework (osf.io/sp3xa/) and an electronic search was carried out in the databas...

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Main Authors: Ana Beatriz Vilela Teixeira, Gabriela Greghi de Carvalho, Andréa Cândido dos Reis
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Saudi Dental Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1013905222000712
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author Ana Beatriz Vilela Teixeira
Gabriela Greghi de Carvalho
Andréa Cândido dos Reis
author_facet Ana Beatriz Vilela Teixeira
Gabriela Greghi de Carvalho
Andréa Cândido dos Reis
author_sort Ana Beatriz Vilela Teixeira
collection DOAJ
description Background: This review aimed to identify antimicrobial agents incorporated into dental materials obtained through additive manufacturing and their efficacy. Methods: Protocol registration was performed in Open Science Framework (osf.io/sp3xa/) and an electronic search was carried out in the databases PubMed, Science Direct, Embase, Lilacs, and Scopus, up to February 2022, combining the terms (“additive manufacturing” OR “3D printing”) AND (antimicrobial). Eligibility criteria included: experimental studies that incorporated 3D printing material with an antimicrobial agent for dental application; that evaluated antimicrobial activity; articles published in peer-reviewed journals and in English. Results: The database search resulted in 1139 references. The manual selection was carried out in 851 studies. Twenty-five articles were selected for full-text reading, of which 8 were included in this review. Polymers were the dental materials most often modified with antimicrobial agents for 3D printing, followed by metal alloy. The antimicrobials used were mainly nanoparticles, metal particles, antifungals, monomers containing quaternary ammonium salt, and antiseptics such as chlorhexidine. Conclusion: The addition of the antimicrobial agents in polymers and alloy for additive manufacturing showed promising efficacy against Candida spp., Gram-positive and Gram-negative bacteria.
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spelling doaj.art-fd08b2dbe40a44908f3b9c4125cdc54a2022-12-22T04:05:06ZengElsevierSaudi Dental Journal1013-90522022-09-01346411420Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature reviewAna Beatriz Vilela Teixeira0Gabriela Greghi de Carvalho1Andréa Cândido dos Reis2Departament of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, Av. Do Café, s/n, 14040-904 Ribeirão Preto, SP, BrazilDepartament of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, Av. Do Café, s/n, 14040-904 Ribeirão Preto, SP, BrazilCorresponding author.; Departament of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, Av. Do Café, s/n, 14040-904 Ribeirão Preto, SP, BrazilBackground: This review aimed to identify antimicrobial agents incorporated into dental materials obtained through additive manufacturing and their efficacy. Methods: Protocol registration was performed in Open Science Framework (osf.io/sp3xa/) and an electronic search was carried out in the databases PubMed, Science Direct, Embase, Lilacs, and Scopus, up to February 2022, combining the terms (“additive manufacturing” OR “3D printing”) AND (antimicrobial). Eligibility criteria included: experimental studies that incorporated 3D printing material with an antimicrobial agent for dental application; that evaluated antimicrobial activity; articles published in peer-reviewed journals and in English. Results: The database search resulted in 1139 references. The manual selection was carried out in 851 studies. Twenty-five articles were selected for full-text reading, of which 8 were included in this review. Polymers were the dental materials most often modified with antimicrobial agents for 3D printing, followed by metal alloy. The antimicrobials used were mainly nanoparticles, metal particles, antifungals, monomers containing quaternary ammonium salt, and antiseptics such as chlorhexidine. Conclusion: The addition of the antimicrobial agents in polymers and alloy for additive manufacturing showed promising efficacy against Candida spp., Gram-positive and Gram-negative bacteria.http://www.sciencedirect.com/science/article/pii/S10139052220007123D printingAdditive manufacturingAntimicrobial agentsAntimicrobial efficacyDental materials
spellingShingle Ana Beatriz Vilela Teixeira
Gabriela Greghi de Carvalho
Andréa Cândido dos Reis
Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review
Saudi Dental Journal
3D printing
Additive manufacturing
Antimicrobial agents
Antimicrobial efficacy
Dental materials
title Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review
title_full Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review
title_fullStr Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review
title_full_unstemmed Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review
title_short Incorporation of antimicrobial agents into dental materials obtained by additive manufacturing: A literature review
title_sort incorporation of antimicrobial agents into dental materials obtained by additive manufacturing a literature review
topic 3D printing
Additive manufacturing
Antimicrobial agents
Antimicrobial efficacy
Dental materials
url http://www.sciencedirect.com/science/article/pii/S1013905222000712
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