A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans

A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans

Recent biochemical experiments have indicated that in Candida albicans, a commensal fungal pathogen, the Ras signaling pathway plays a significant role in the yeast‐to‐hyphal transition; specifically, two enzymes in this pathway, Adenyl Cyclase Cyr1 and GTPase activating protein Ira2, facilitate thi...

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Bibliographic Details
Main Author:	K Sriram
Format:	Article
Language:	English
Published:	Wiley 2022-10-01
Series:	FEBS Open Bio
Subjects:	bistable Candida albicans ODE positive feedback Ras signaling pathway yeast‐hyphal switching
Online Access:	https://doi.org/10.1002/2211-5463.13470

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