Multiplex live single-cell transcriptional analysis demarcates cellular functional heterogeneity

Multiplex live single-cell transcriptional analysis demarcates cellular functional heterogeneity

A fundamental goal in the biological sciences is to determine how individual cells with varied gene expression profiles and diverse functional characteristics contribute to development, physiology, and disease. Here, we report a novel strategy to assess gene expression and cell physiology in single...

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Bibliographic Details
Main Authors: Ayhan Atmanli, Dongjian Hu, Frederik Ernst Deiman, Annebel Marjolein van de Vrugt, François Cherbonneau, Lauren Deems Black III, Ibrahim John Domian
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
pluripotent stem cells
cellular differentiation
lineage diversification
cellular heterogeneity
single-cell physiology
FRET
Online Access:https://elifesciences.org/articles/49599

Internet

https://elifesciences.org/articles/49599

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