Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids?
The Mediterranean diet is characterized by a high consumption of fruits, vegetables, legumes, cereals, and olive oil as the main source of added fat, a moderate consumption of fish and wine, and a low consumption of meat and dairy products as a source of saturated fat. Several epidemiological studie...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2011-07-01
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| Series: | Oléagineux, Corps gras, Lipides |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1051/ocl.2011.0388 |
| _version_ | 1818352727061692416 |
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| author | Barberger-Gateau Pascale Féart Catherine Samieri Cécilia |
| author_facet | Barberger-Gateau Pascale Féart Catherine Samieri Cécilia |
| author_sort | Barberger-Gateau Pascale |
| collection | DOAJ |
| description | The Mediterranean diet is characterized by a high consumption of fruits, vegetables, legumes, cereals, and olive oil as the main source of added fat, a moderate consumption of fish and wine, and a low consumption of meat and dairy products as a source of saturated fat. Several epidemiological studies have shown that higher adherence to a Mediterranean diet was associated with slower cognitive decline in older persons. This protective effect might be mediated by omega-3 poly-unsaturated fatty acids (n-3 PUFA). We investigated this hypothesis in 1050 participants in the 3City study from Bordeaux. After multivariable adjustment including apolipoprotein E (ApoE) genotype, plasma docosahexaenoic acid and total n-3 PUFA were positively associated with a score of adherence to a Mediterranean diet. Plasma eicosapentaenoic acid was positively associated with adherence only in ApoE4 non-carriers. These data suggest that the protective effect of the Mediterranean diet on cognitive functions might be partly mediated by higher plasma n-3 PUFA. |
| first_indexed | 2024-12-13T18:58:13Z |
| format | Article |
| id | doaj.art-fd1353ab51b74b6c9e157d618ed4b763 |
| institution | Directory Open Access Journal |
| issn | 1258-8210 1950-697X |
| language | English |
| last_indexed | 2024-12-13T18:58:13Z |
| publishDate | 2011-07-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Oléagineux, Corps gras, Lipides |
| spelling | doaj.art-fd1353ab51b74b6c9e157d618ed4b7632022-12-21T23:34:45ZengEDP SciencesOléagineux, Corps gras, Lipides1258-82101950-697X2011-07-0118422422710.1051/ocl.2011.0388ocl2011184p224Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids?Barberger-Gateau PascaleFéart CatherineSamieri CéciliaThe Mediterranean diet is characterized by a high consumption of fruits, vegetables, legumes, cereals, and olive oil as the main source of added fat, a moderate consumption of fish and wine, and a low consumption of meat and dairy products as a source of saturated fat. Several epidemiological studies have shown that higher adherence to a Mediterranean diet was associated with slower cognitive decline in older persons. This protective effect might be mediated by omega-3 poly-unsaturated fatty acids (n-3 PUFA). We investigated this hypothesis in 1050 participants in the 3City study from Bordeaux. After multivariable adjustment including apolipoprotein E (ApoE) genotype, plasma docosahexaenoic acid and total n-3 PUFA were positively associated with a score of adherence to a Mediterranean diet. Plasma eicosapentaenoic acid was positively associated with adherence only in ApoE4 non-carriers. These data suggest that the protective effect of the Mediterranean diet on cognitive functions might be partly mediated by higher plasma n-3 PUFA.http://dx.doi.org/10.1051/ocl.2011.0388dietcognitionagingfatty acidsomega-3mediterranean diet |
| spellingShingle | Barberger-Gateau Pascale Féart Catherine Samieri Cécilia Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids? Oléagineux, Corps gras, Lipides diet cognition aging fatty acids omega-3 mediterranean diet |
| title | Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids? |
| title_full | Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids? |
| title_fullStr | Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids? |
| title_full_unstemmed | Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids? |
| title_short | Mediterranean diet and cognitive decline: what role for omega-3 polyunsaturated fatty acids? |
| title_sort | mediterranean diet and cognitive decline what role for omega 3 polyunsaturated fatty acids |
| topic | diet cognition aging fatty acids omega-3 mediterranean diet |
| url | http://dx.doi.org/10.1051/ocl.2011.0388 |
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