Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127
PurposeInvestigation of the community-level symptomatic onset risk regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, is crucial to the pandemic control in the new normal.MethodsInvestigated in this study is the spatiotemporal symptom onset risk with Omicron...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-09-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.978052/full |
| _version_ | 1811260827265662976 |
|---|---|
| author | Chengzhuo Tong Wenzhong Shi Gilman Kit-Hang Siu Anshu Zhang Zhicheng Shi |
| author_facet | Chengzhuo Tong Wenzhong Shi Gilman Kit-Hang Siu Anshu Zhang Zhicheng Shi |
| author_sort | Chengzhuo Tong |
| collection | DOAJ |
| description | PurposeInvestigation of the community-level symptomatic onset risk regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, is crucial to the pandemic control in the new normal.MethodsInvestigated in this study is the spatiotemporal symptom onset risk with Omicron BA.1, BA.2, and hamster-related Delta AY.127 by a joint analysis of community-based human mobility, virus genomes, and vaccinations in Hong Kong.ResultsThe spatial spread of Omicron BA.2 was found to be 2.91 times and 2.56 times faster than that of Omicron BA.1 and Delta AY.127. Identified has been an early spatial invasion process in which spatiotemporal symptom onset risk was associated with intercommunity and cross-community human mobility of a dominant source location, especially regarding enhancement of the effects of the increased intrinsic transmissibility of Omicron BA.2. Further explored is the spread of Omicron BA.1, BA.2, and Delta AY.127 under different full and booster vaccination rate levels. An increase in full vaccination rates has primarily contributed to the reduction in areas within lower onset risk. An increase in the booster vaccination rate can promote a reduction in those areas within higher onset risk.ConclusionsThis study has provided a comprehensive investigation concerning the spatiotemporal symptom onset risk of Omicron BA.1, BA.2, and hamster-related Delta AY.127, and as such can contribute some help to countries and regions regarding the prevention of the emergence of such as these variants, on a strategic basis. Moreover, this study provides scientifically derived findings on the impact of full and booster vaccination campaigns working in the area of the reduction of symptomatic infections. |
| first_indexed | 2024-04-12T18:53:29Z |
| format | Article |
| id | doaj.art-fd16a11b2bb54dba84c2f86d79b9a92b |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-12T18:53:29Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-fd16a11b2bb54dba84c2f86d79b9a92b2022-12-22T03:20:24ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-09-011010.3389/fpubh.2022.978052978052Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127Chengzhuo Tong0Wenzhong Shi1Gilman Kit-Hang Siu2Anshu Zhang3Zhicheng Shi4Department of Land Surveying and Geo-Informatics, Otto Poon Charitable Foundation Smart Cities Research Institute, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, ChinaDepartment of Land Surveying and Geo-Informatics, Otto Poon Charitable Foundation Smart Cities Research Institute, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, ChinaDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, ChinaDepartment of Land Surveying and Geo-Informatics, Otto Poon Charitable Foundation Smart Cities Research Institute, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, ChinaResearch Institute for Smart Cities, School of Architecture and Urban Planning, Shenzhen University, Shenzhen, ChinaPurposeInvestigation of the community-level symptomatic onset risk regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, is crucial to the pandemic control in the new normal.MethodsInvestigated in this study is the spatiotemporal symptom onset risk with Omicron BA.1, BA.2, and hamster-related Delta AY.127 by a joint analysis of community-based human mobility, virus genomes, and vaccinations in Hong Kong.ResultsThe spatial spread of Omicron BA.2 was found to be 2.91 times and 2.56 times faster than that of Omicron BA.1 and Delta AY.127. Identified has been an early spatial invasion process in which spatiotemporal symptom onset risk was associated with intercommunity and cross-community human mobility of a dominant source location, especially regarding enhancement of the effects of the increased intrinsic transmissibility of Omicron BA.2. Further explored is the spread of Omicron BA.1, BA.2, and Delta AY.127 under different full and booster vaccination rate levels. An increase in full vaccination rates has primarily contributed to the reduction in areas within lower onset risk. An increase in the booster vaccination rate can promote a reduction in those areas within higher onset risk.ConclusionsThis study has provided a comprehensive investigation concerning the spatiotemporal symptom onset risk of Omicron BA.1, BA.2, and hamster-related Delta AY.127, and as such can contribute some help to countries and regions regarding the prevention of the emergence of such as these variants, on a strategic basis. Moreover, this study provides scientifically derived findings on the impact of full and booster vaccination campaigns working in the area of the reduction of symptomatic infections.https://www.frontiersin.org/articles/10.3389/fpubh.2022.978052/fullOmicron BA.1 and BA.2hamster-related Delta AY.127spatiotemporal symptom onset riskfull vaccinationbooster vaccination |
| spellingShingle | Chengzhuo Tong Wenzhong Shi Gilman Kit-Hang Siu Anshu Zhang Zhicheng Shi Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127 Frontiers in Public Health Omicron BA.1 and BA.2 hamster-related Delta AY.127 spatiotemporal symptom onset risk full vaccination booster vaccination |
| title | Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127 |
| title_full | Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127 |
| title_fullStr | Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127 |
| title_full_unstemmed | Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127 |
| title_short | Understanding spatiotemporal symptom onset risk of Omicron BA.1, BA.2 and hamster-related Delta AY.127 |
| title_sort | understanding spatiotemporal symptom onset risk of omicron ba 1 ba 2 and hamster related delta ay 127 |
| topic | Omicron BA.1 and BA.2 hamster-related Delta AY.127 spatiotemporal symptom onset risk full vaccination booster vaccination |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.978052/full |
| work_keys_str_mv | AT chengzhuotong understandingspatiotemporalsymptomonsetriskofomicronba1ba2andhamsterrelateddeltaay127 AT wenzhongshi understandingspatiotemporalsymptomonsetriskofomicronba1ba2andhamsterrelateddeltaay127 AT gilmankithangsiu understandingspatiotemporalsymptomonsetriskofomicronba1ba2andhamsterrelateddeltaay127 AT anshuzhang understandingspatiotemporalsymptomonsetriskofomicronba1ba2andhamsterrelateddeltaay127 AT zhichengshi understandingspatiotemporalsymptomonsetriskofomicronba1ba2andhamsterrelateddeltaay127 |