Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer

Esophageal cancer is one of the malignant tumors with poor prognosis in China. Currently, the treatment of esophageal cancer is still based on surgery, especially in early and mid-stage patients, to achieve the goal of radical cure. However, esophageal cancer is a kind of tumor with a high risk of r...

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Main Authors: Yujie Zhang, Yuxin Zhang, Lin Peng, Li Zhang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/1/114
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author Yujie Zhang
Yuxin Zhang
Lin Peng
Li Zhang
author_facet Yujie Zhang
Yuxin Zhang
Lin Peng
Li Zhang
author_sort Yujie Zhang
collection DOAJ
description Esophageal cancer is one of the malignant tumors with poor prognosis in China. Currently, the treatment of esophageal cancer is still based on surgery, especially in early and mid-stage patients, to achieve the goal of radical cure. However, esophageal cancer is a kind of tumor with a high risk of recurrence and metastasis, and locoregional recurrence and distant metastasis are the leading causes of death after surgery. Although multimodal comprehensive treatment has advanced in recent years, the prediction, prevention and treatment of postoperative recurrence and metastasis of esophageal cancer are still unsatisfactory. How to reduce recurrence and metastasis in patients after surgery remains an urgent problem to be solved. Given the clinical demand for early detection of postoperative recurrence of esophageal cancer, clinical and basic research aiming to meet this demand has been a hot topic, and progress has been observed in recent years. Therefore, this article reviews the research progress on the factors that influence and predict postoperative recurrence of esophageal cancer, hoping to provide new research directions and treatment strategies for clinical practice.
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spelling doaj.art-fd1e834052304e73bceba127c456ac7f2023-11-16T15:06:17ZengMDPI AGCells2073-44092022-12-0112111410.3390/cells12010114Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal CancerYujie Zhang0Yuxin Zhang1Lin Peng2Li Zhang3Department of Oncology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, ChinaDepartment of Pediatric Surgery, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, ChinaDepartment of Oncology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, ChinaDepartment of Oncology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, No. 1095 Jiefang Avenue, Wuhan 430030, ChinaEsophageal cancer is one of the malignant tumors with poor prognosis in China. Currently, the treatment of esophageal cancer is still based on surgery, especially in early and mid-stage patients, to achieve the goal of radical cure. However, esophageal cancer is a kind of tumor with a high risk of recurrence and metastasis, and locoregional recurrence and distant metastasis are the leading causes of death after surgery. Although multimodal comprehensive treatment has advanced in recent years, the prediction, prevention and treatment of postoperative recurrence and metastasis of esophageal cancer are still unsatisfactory. How to reduce recurrence and metastasis in patients after surgery remains an urgent problem to be solved. Given the clinical demand for early detection of postoperative recurrence of esophageal cancer, clinical and basic research aiming to meet this demand has been a hot topic, and progress has been observed in recent years. Therefore, this article reviews the research progress on the factors that influence and predict postoperative recurrence of esophageal cancer, hoping to provide new research directions and treatment strategies for clinical practice.https://www.mdpi.com/2073-4409/12/1/114esophageal cancerpostoperative recurrencemetastasisclinical biomarkersmolecular markers
spellingShingle Yujie Zhang
Yuxin Zhang
Lin Peng
Li Zhang
Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer
Cells
esophageal cancer
postoperative recurrence
metastasis
clinical biomarkers
molecular markers
title Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer
title_full Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer
title_fullStr Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer
title_full_unstemmed Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer
title_short Research Progress on the Predicting Factors and Coping Strategies for Postoperative Recurrence of Esophageal Cancer
title_sort research progress on the predicting factors and coping strategies for postoperative recurrence of esophageal cancer
topic esophageal cancer
postoperative recurrence
metastasis
clinical biomarkers
molecular markers
url https://www.mdpi.com/2073-4409/12/1/114
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