Resective surgery versus palliative care in advanced gallbladder cancer
INTRODUCTION Despite multiple advances in medicine, gallbladder cancer remains a disease with poor prognosis. In advanced stages, the main options are surgical management or palliative non-surgical care. However, it is not clear which therapy constitutes a better alternative. METHODS We searche...
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| Format: | Article |
| Language: | English |
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Medwave Estudios Limitada
2019-11-01
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| Series: | Medwave |
| Subjects: | |
| Online Access: | https://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/7730 |
| _version_ | 1811229578553720832 |
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| author | Jai-sen Leung Eduardo Viñuela |
| author_facet | Jai-sen Leung Eduardo Viñuela |
| author_sort | Jai-sen Leung |
| collection | DOAJ |
| description | INTRODUCTION
Despite multiple advances in medicine, gallbladder cancer remains a disease with poor prognosis. In advanced stages, the main options are surgical management or palliative non-surgical care. However, it is not clear which therapy constitutes a better alternative.
METHODS
We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach.
RESULTS AND CONCLUSIONS
We identified one systematic review including three primary studies, none of them randomized. We concluded that resective surgery may increase survival rates in patients with advanced gallbladder cancer, but the certainty of the evidence is low. |
| first_indexed | 2024-04-12T10:16:31Z |
| format | Article |
| id | doaj.art-fd2137c5971841c0ae2a0afa9353af0c |
| institution | Directory Open Access Journal |
| issn | 0717-6384 |
| language | English |
| last_indexed | 2024-04-12T10:16:31Z |
| publishDate | 2019-11-01 |
| publisher | Medwave Estudios Limitada |
| record_format | Article |
| series | Medwave |
| spelling | doaj.art-fd2137c5971841c0ae2a0afa9353af0c2022-12-22T03:37:11ZengMedwave Estudios LimitadaMedwave0717-63842019-11-011910e7725e772510.5867/medwave.2019.10.7725Resective surgery versus palliative care in advanced gallbladder cancerJai-sen Leung0Eduardo Viñuela1Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, Chile.Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, Chile.INTRODUCTION Despite multiple advances in medicine, gallbladder cancer remains a disease with poor prognosis. In advanced stages, the main options are surgical management or palliative non-surgical care. However, it is not clear which therapy constitutes a better alternative. METHODS We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach. RESULTS AND CONCLUSIONS We identified one systematic review including three primary studies, none of them randomized. We concluded that resective surgery may increase survival rates in patients with advanced gallbladder cancer, but the certainty of the evidence is low.https://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/7730advanced gallbladder cancerresective surgerypalliativeepistemonikosgrade |
| spellingShingle | Jai-sen Leung Eduardo Viñuela Resective surgery versus palliative care in advanced gallbladder cancer Medwave advanced gallbladder cancer resective surgery palliative epistemonikos grade |
| title | Resective surgery versus palliative care in advanced gallbladder cancer |
| title_full | Resective surgery versus palliative care in advanced gallbladder cancer |
| title_fullStr | Resective surgery versus palliative care in advanced gallbladder cancer |
| title_full_unstemmed | Resective surgery versus palliative care in advanced gallbladder cancer |
| title_short | Resective surgery versus palliative care in advanced gallbladder cancer |
| title_sort | resective surgery versus palliative care in advanced gallbladder cancer |
| topic | advanced gallbladder cancer resective surgery palliative epistemonikos grade |
| url | https://www.medwave.cl/link.cgi/Medwave/PuestaDia/ResEpis/7730 |
| work_keys_str_mv | AT jaisenleung resectivesurgeryversuspalliativecareinadvancedgallbladdercancer AT eduardovinuela resectivesurgeryversuspalliativecareinadvancedgallbladdercancer |