Sustained spike-specific IgG antibodies following CoronaVac (Sinovac) vaccination in sub-Saharan Africa, but increased breakthrough infections in baseline spike-naive individuals

Sustained spike-specific IgG antibodies following CoronaVac (Sinovac) vaccination in sub-Saharan Africa, but increased breakthrough infections in baseline spike-naive individuals

IntroductionThis study investigated the antibody responses to the inactivated COVID-19 vaccine, CoronaVac (Sinovac Biotech) in the African population to provide valuable insights into long-term immunity and breakthrough infections against SARS-CoV-2 in individuals with varying prior IgG seropositivi...

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Bibliographic Details
Main Authors:	Jackson Sembera, Claire Baine, Violet Ankunda, Joseph Ssebwana Katende, Gerald Kevin Oluka, Christine Hermilia Akoli, Laban Kato, Geoffrey Odoch, Peter Ejou, Solomon Opio, Monica Musenero, The COVID-19 Immunoprofiling Team, Pontiano Kaleebu, Jennifer Serwanga
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Immunology
Subjects:	CoronaVac COVID-19 antibody concentrations seropositivity antibody persistence breakthrough infections
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1255676/full

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