Role of the ITAM-Bearing Receptors Expressed by Natural Killer Cells in Cancer

Role of the ITAM-Bearing Receptors Expressed by Natural Killer Cells in Cancer

Natural Killer (NK) cells are innate lymphoid cells (ILCs) capable of recognizing and directly killing tumor cells. They also secrete cytokines and chemokines, which participate in the shaping of the adaptive response. NK cells identify tumor cells and are activated through a net positive signal fro...

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Bibliographic Details
Main Authors: Hakim Medjouel Khlifi, Sophie Guia, Eric Vivier, Emilie Narni-Mancinelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
NK cells
ITAM
cancer
NCR
activating receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.898745/full

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