INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL
There were 81 patients with vertebral canal stenosis under observation. All patients underwent complex examination: study of clinical neurological status; review spondylography of lumbar part of the spine; MRI of lumbar part of the spine; multispiral CT with myelography of lumbar part of the spine;...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2013-04-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1440 |
| _version_ | 1797237589344780288 |
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| author | Z. V. Koshkariova V. A. Sorokovikov A. V. Gorbunov V. G. Brukhanov L. V. Rodionova O. V. Skliarenko |
| author_facet | Z. V. Koshkariova V. A. Sorokovikov A. V. Gorbunov V. G. Brukhanov L. V. Rodionova O. V. Skliarenko |
| author_sort | Z. V. Koshkariova |
| collection | DOAJ |
| description | There were 81 patients with vertebral canal stenosis under observation. All patients underwent complex examination: study of clinical neurological status; review spondylography of lumbar part of the spine; MRI of lumbar part of the spine; multispiral CT with myelography of lumbar part of the spine; functional spondylography of lumbar part of the spine with load; the study of morphometry of vertebral canal, dural sack and vertebra body by designed method; the study of acute phase proteins in blood. Conducted complex research revealed that improved classification of stenosis of vertebral canal reflects direct dependence of severity of clinical-neurological manifestations from the degree of stenosis. It also has been marked that reduced concentration of α2-macroglobulin in blood manifests itself in negative regulation of cells of immune system. And an increase of classic rheumatoid factor (Ig M-RF), α1-antitripsin and α1-acid glycoprotein in blood serum leads to reduction of inflammatory and immune response. Revealed direct co-dependence of severity of disease and degree of stenosis gives a possibility to develop more precise program of conservative and surgical treatment. |
| first_indexed | 2024-03-08T12:21:27Z |
| format | Article |
| id | doaj.art-fd286d614fd1455a97dfd3b5dc59c52e |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2024-04-24T17:22:09Z |
| publishDate | 2013-04-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-fd286d614fd1455a97dfd3b5dc59c52e2024-03-28T07:49:09ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962013-04-0102(2)29331386INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVELZ. V. Koshkariova0V. A. Sorokovikov1A. V. Gorbunov2V. G. Brukhanov3L. V. Rodionova4O. V. Skliarenko5Scientific Center of Reconstructive and Restorative Surgery SB RAMSScientific Center of Reconstructive and Restorative Surgery SB RAMS; Irkutsk State Medical Academy of Continuing EdicationScientific Center of Reconstructive and Restorative Surgery SB RAMSScientific Center of Reconstructive and Restorative Surgery SB RAMSScientific Center of Reconstructive and Restorative Surgery SB RAMSScientific Center of Reconstructive and Restorative Surgery SB RAMSThere were 81 patients with vertebral canal stenosis under observation. All patients underwent complex examination: study of clinical neurological status; review spondylography of lumbar part of the spine; MRI of lumbar part of the spine; multispiral CT with myelography of lumbar part of the spine; functional spondylography of lumbar part of the spine with load; the study of morphometry of vertebral canal, dural sack and vertebra body by designed method; the study of acute phase proteins in blood. Conducted complex research revealed that improved classification of stenosis of vertebral canal reflects direct dependence of severity of clinical-neurological manifestations from the degree of stenosis. It also has been marked that reduced concentration of α2-macroglobulin in blood manifests itself in negative regulation of cells of immune system. And an increase of classic rheumatoid factor (Ig M-RF), α1-antitripsin and α1-acid glycoprotein in blood serum leads to reduction of inflammatory and immune response. Revealed direct co-dependence of severity of disease and degree of stenosis gives a possibility to develop more precise program of conservative and surgical treatment.https://www.actabiomedica.ru/jour/article/view/1440osteochondrosisstenosisvertebral canalclinical-neurological syndromesacute phase proteins of blood |
| spellingShingle | Z. V. Koshkariova V. A. Sorokovikov A. V. Gorbunov V. G. Brukhanov L. V. Rodionova O. V. Skliarenko INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL Acta Biomedica Scientifica osteochondrosis stenosis vertebral canal clinical-neurological syndromes acute phase proteins of blood |
| title | INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL |
| title_full | INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL |
| title_fullStr | INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL |
| title_full_unstemmed | INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL |
| title_short | INTERRELATION AND INTERDEPENDENCE OF CLINICAL SYNDROMES FROM DEGREE OF STENOSIS OF VERTEBRAL CANAL ON LUMBAR LEVEL |
| title_sort | interrelation and interdependence of clinical syndromes from degree of stenosis of vertebral canal on lumbar level |
| topic | osteochondrosis stenosis vertebral canal clinical-neurological syndromes acute phase proteins of blood |
| url | https://www.actabiomedica.ru/jour/article/view/1440 |
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