Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: a genome-wide association study.
Fifty percent of variability in HIV-1 susceptibility is attributable to host genetics. Thus identifying genetic associations is essential to understanding pathogenesis of HIV-1 and important for targeting drug development. To date, however, CCR5 remains the only gene conclusively associated with HIV...
Main Authors: | Eric O Johnson, Dana B Hancock, Nathan C Gaddis, Joshua L Levy, Grier Page, Scott P Novak, Cristie Glasheen, Nancy L Saccone, John P Rice, Michael P Moreau, Kimberly F Doheny, Jane M Romm, Andrew I Brooks, Bradley E Aouizerat, Laura J Bierut, Alex H Kral |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4364715?pdf=render |
Similar Items
-
HIV control through a single nucleotide on the HLA-I locus
by: Kloverpris, H, et al.
Published: (2012) -
Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive predictive value
by: Amy Moore, et al.
Published: (2023-11-01) -
HIV control through a single nucleotide on the HLA-B locus.
by: Kløverpris, H, et al.
Published: (2012) -
The receptor for HIV: dissection of CD4 and studies on putative accessory factors.
by: James, W, et al.
Published: (1996) -
Identification and characterization of a nontypeable <it>Haemophilus influenzae </it>putative toxin-antitoxin locus
by: Smith Arnold L, et al.
Published: (2004-07-01)