Going Natural: Using polymers from nature for gastroresistant applications

Nutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions. Nutraceuticals contain natural ingredients, usually presented in the form of functional foods or as dietary supplements....

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Bibliographic Details
Main Authors: Joao Barbosa, Barbara Conway, Hamid Merchant
Format: Article
Language:English
Published: University of Huddersfield Press 2017-07-01
Series:British Journal of Pharmacy
Online Access:https://www.bjpharm.org.uk/article/id/30/
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author Joao Barbosa
Barbara Conway
Hamid Merchant
author_facet Joao Barbosa
Barbara Conway
Hamid Merchant
author_sort Joao Barbosa
collection DOAJ
description Nutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions. Nutraceuticals contain natural ingredients, usually presented in the form of functional foods or as dietary supplements. Many of the ingredients are susceptible to degradation by gastric acid or can provoke nauseatic feelings or induce vomiting on oral administration. Gastroresistant coatings, widely researched and used in pharmaceuticals, employ enteric polymers which are not regarded as natural ingredients or do not possess GRAS (generally regarded as safe) status by the regulatory bodies, thus cannot be used for nutraceutical products. Consequently, most nutraceuticals are not formulated as gastroresistant and can therefore lack efficacy or are well tolerated. This manuscript provides a critical review of natural substances employed in producing gastroresistant products, their shortcomings, and potential industrial applications. It also identifies current gaps in our knowledge to encourage further research in this area.
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spelling doaj.art-fd2a62b115fd4ced8b2d9197916bf0882023-05-23T14:57:21ZengUniversity of Huddersfield PressBritish Journal of Pharmacy2058-83562017-07-012110.5920/bjpharm.2017.01Going Natural: Using polymers from nature for gastroresistant applicationsJoao Barbosa0Barbara Conway1Hamid Merchant2University of HuddersfieldUniversity of HuddersfieldUniversity of HuddersfieldNutraceuticals provide an additional health or medicinal benefit besides their nutritional value and are therefore marketed for the prevention and treatment of certain conditions. Nutraceuticals contain natural ingredients, usually presented in the form of functional foods or as dietary supplements. Many of the ingredients are susceptible to degradation by gastric acid or can provoke nauseatic feelings or induce vomiting on oral administration. Gastroresistant coatings, widely researched and used in pharmaceuticals, employ enteric polymers which are not regarded as natural ingredients or do not possess GRAS (generally regarded as safe) status by the regulatory bodies, thus cannot be used for nutraceutical products. Consequently, most nutraceuticals are not formulated as gastroresistant and can therefore lack efficacy or are well tolerated. This manuscript provides a critical review of natural substances employed in producing gastroresistant products, their shortcomings, and potential industrial applications. It also identifies current gaps in our knowledge to encourage further research in this area.https://www.bjpharm.org.uk/article/id/30/
spellingShingle Joao Barbosa
Barbara Conway
Hamid Merchant
Going Natural: Using polymers from nature for gastroresistant applications
British Journal of Pharmacy
title Going Natural: Using polymers from nature for gastroresistant applications
title_full Going Natural: Using polymers from nature for gastroresistant applications
title_fullStr Going Natural: Using polymers from nature for gastroresistant applications
title_full_unstemmed Going Natural: Using polymers from nature for gastroresistant applications
title_short Going Natural: Using polymers from nature for gastroresistant applications
title_sort going natural using polymers from nature for gastroresistant applications
url https://www.bjpharm.org.uk/article/id/30/
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AT barbaraconway goingnaturalusingpolymersfromnatureforgastroresistantapplications
AT hamidmerchant goingnaturalusingpolymersfromnatureforgastroresistantapplications