Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly
Abstract Background P‐wave dispersion (PWD) is believed to be caused by inhomogeneous atrial conduction. This statement, however, is based on limited little solid evidence. The aim of this study was to determine the relationship between atrial conduction and PWD by means of invasive electrophysiolog...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-12-01
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| Series: | Journal of Arrhythmia |
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| Online Access: | https://doi.org/10.1002/joa3.12444 |
| _version_ | 1819160559987195904 |
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| author | Raimundo Carmona Puerta Elibet Chávez González Magda Alina Rabassa López‐Calleja Elizabeth Lorenzo Martínez Juan Miguel Cruz Elizundia Gustavo Padrón Peña Fernando Rodríguez González |
| author_facet | Raimundo Carmona Puerta Elibet Chávez González Magda Alina Rabassa López‐Calleja Elizabeth Lorenzo Martínez Juan Miguel Cruz Elizundia Gustavo Padrón Peña Fernando Rodríguez González |
| author_sort | Raimundo Carmona Puerta |
| collection | DOAJ |
| description | Abstract Background P‐wave dispersion (PWD) is believed to be caused by inhomogeneous atrial conduction. This statement, however, is based on limited little solid evidence. The aim of this study was to determine the relationship between atrial conduction and PWD by means of invasive electrophysiological studies. Methods Cross‐sectional study in 153 patients with accessory pathways and atrioventricular node reentry tachycardia (AVNRT) undergoing an electrophysiological study. Different atrial conduction times were measured and correlated with PWD. Results Only the interatrial (P‐DCS) and left intra‐atrial conduction times (ΔDCS‐PCS) showed a significant correlation with PWD, but this correlation was weak. Multivariate linear regression analysis determined that both P‐DCS (β = 0.242; P = .008) and ΔDCS‐PCS (β = 0.295; P < .001) are independent predictors of PWD. Performing the multivariate analysis for arrhythmic substrates, it is observed that only ΔDCS‐PCS continued to be an independent predictor of PWD. Analysis of the receiver operating characteristic curves showed that regardless of the types of arrhythmic substrates, PWD discriminates significantly, but moderately, to patients with P‐DCS and ΔDCS‐PCS ≥75 percentile. Conclusions Interatrial and intraleft atrial conduction times were directly and significantly correlated with PWD, but only weakly, and were independent predictors of PWD. In general, PWD correctly discriminates patients with high values in interatrial and intraleft atrial conduction times, but moderately. This is maintained in cases with accessory pathways; however, in patients with AVNRT it only does so for intraleft atrial conduction times. Interatrial and intraleft atrial conduction times weakly explains PWD. |
| first_indexed | 2024-12-22T16:58:23Z |
| format | Article |
| id | doaj.art-fd2b44db2cfa45bab02ea8ee53a2341b |
| institution | Directory Open Access Journal |
| issn | 1880-4276 1883-2148 |
| language | English |
| last_indexed | 2024-12-22T16:58:23Z |
| publishDate | 2020-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Arrhythmia |
| spelling | doaj.art-fd2b44db2cfa45bab02ea8ee53a2341b2022-12-21T18:19:24ZengWileyJournal of Arrhythmia1880-42761883-21482020-12-013661083109110.1002/joa3.12444Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weaklyRaimundo Carmona Puerta0Elibet Chávez González1Magda Alina Rabassa López‐Calleja2Elizabeth Lorenzo Martínez3Juan Miguel Cruz Elizundia4Gustavo Padrón Peña5Fernando Rodríguez González6Department of Electrophysiology and Arrhythmology Cardiovascular Hospital "Ernesto Guevara" Santa Clara City CubaDepartment of Electrophysiology and Arrhythmology Cardiovascular Hospital "Ernesto Guevara" Santa Clara City CubaChief Professor in Cardiology Cardiovascular Hospital "Ernesto Guevara" Santa Clara City CubaDepartment of Physiology Medical University of Villa Clara Santa Clara City CubaDepartment of Electrophysiology and Arrhythmology Cardiovascular Hospital "Ernesto Guevara" Santa Clara City CubaDepartment of Electrophysiology and Arrhythmology Cardiovascular Hospital "Ernesto Guevara" Santa Clara City CubaDepartment of Electrophysiology and Arrhythmology Cardiovascular Hospital "Ernesto Guevara" Santa Clara City CubaAbstract Background P‐wave dispersion (PWD) is believed to be caused by inhomogeneous atrial conduction. This statement, however, is based on limited little solid evidence. The aim of this study was to determine the relationship between atrial conduction and PWD by means of invasive electrophysiological studies. Methods Cross‐sectional study in 153 patients with accessory pathways and atrioventricular node reentry tachycardia (AVNRT) undergoing an electrophysiological study. Different atrial conduction times were measured and correlated with PWD. Results Only the interatrial (P‐DCS) and left intra‐atrial conduction times (ΔDCS‐PCS) showed a significant correlation with PWD, but this correlation was weak. Multivariate linear regression analysis determined that both P‐DCS (β = 0.242; P = .008) and ΔDCS‐PCS (β = 0.295; P < .001) are independent predictors of PWD. Performing the multivariate analysis for arrhythmic substrates, it is observed that only ΔDCS‐PCS continued to be an independent predictor of PWD. Analysis of the receiver operating characteristic curves showed that regardless of the types of arrhythmic substrates, PWD discriminates significantly, but moderately, to patients with P‐DCS and ΔDCS‐PCS ≥75 percentile. Conclusions Interatrial and intraleft atrial conduction times were directly and significantly correlated with PWD, but only weakly, and were independent predictors of PWD. In general, PWD correctly discriminates patients with high values in interatrial and intraleft atrial conduction times, but moderately. This is maintained in cases with accessory pathways; however, in patients with AVNRT it only does so for intraleft atrial conduction times. Interatrial and intraleft atrial conduction times weakly explains PWD.https://doi.org/10.1002/joa3.12444atrial conduction timeelectrophysiological studymaximum P‐wave durationP‐wave dispersion |
| spellingShingle | Raimundo Carmona Puerta Elibet Chávez González Magda Alina Rabassa López‐Calleja Elizabeth Lorenzo Martínez Juan Miguel Cruz Elizundia Gustavo Padrón Peña Fernando Rodríguez González Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly Journal of Arrhythmia atrial conduction time electrophysiological study maximum P‐wave duration P‐wave dispersion |
| title | Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly |
| title_full | Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly |
| title_fullStr | Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly |
| title_full_unstemmed | Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly |
| title_short | Atrial conduction explains the occurrence of the P‐wave dispersion phenomenon, but weakly |
| title_sort | atrial conduction explains the occurrence of the p wave dispersion phenomenon but weakly |
| topic | atrial conduction time electrophysiological study maximum P‐wave duration P‐wave dispersion |
| url | https://doi.org/10.1002/joa3.12444 |
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