Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles

The efficient one-pot synthesis of some 1,4-dihydropyridines is described by a condensation reaction of some aldehyde derivatives, ethyl acetoacetate and ammonium acetate in the presence of superparamagnetic manganese ferrite nanoparticles at 80 °C. The advantages of this protocol include selectivit...

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Main Authors: Somayeh Moradi, Mohsen Moradian, Hossein Naeimi
Format: Article
Language:English
Published: Slovenian Chemical Society 2022-06-01
Series:Acta Chimica Slovenica
Subjects:
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/7238
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author Somayeh Moradi
Mohsen Moradian
Hossein Naeimi
author_facet Somayeh Moradi
Mohsen Moradian
Hossein Naeimi
author_sort Somayeh Moradi
collection DOAJ
description The efficient one-pot synthesis of some 1,4-dihydropyridines is described by a condensation reaction of some aldehyde derivatives, ethyl acetoacetate and ammonium acetate in the presence of superparamagnetic manganese ferrite nanoparticles at 80 °C. The advantages of this protocol include selectivity, high purity of the products, excellent yields, short reaction times, ease of processing, and environmentally friendly conditions for the synthesis of 1,4-dihydropyridines. In addition, the catalyst can be recovered and reused in multiple runs without significantly reducing the product yield.
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spelling doaj.art-fd2c1d562c414a539aeff42e6d100f482023-01-03T11:28:42ZengSlovenian Chemical SocietyActa Chimica Slovenica1318-02071580-31552022-06-0169234935810.17344/acsi.2021.72381081Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 NanoparticlesSomayeh Moradi0Mohsen Moradian1Hossein Naeimi2Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, IranThe efficient one-pot synthesis of some 1,4-dihydropyridines is described by a condensation reaction of some aldehyde derivatives, ethyl acetoacetate and ammonium acetate in the presence of superparamagnetic manganese ferrite nanoparticles at 80 °C. The advantages of this protocol include selectivity, high purity of the products, excellent yields, short reaction times, ease of processing, and environmentally friendly conditions for the synthesis of 1,4-dihydropyridines. In addition, the catalyst can be recovered and reused in multiple runs without significantly reducing the product yield.https://journals.matheo.si/index.php/ACSi/article/view/72381,4-dihydropyridinemnfe2o4nanoparticlescatalystsuperparamagnetism
spellingShingle Somayeh Moradi
Mohsen Moradian
Hossein Naeimi
Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles
Acta Chimica Slovenica
1,4-dihydropyridine
mnfe2o4
nanoparticles
catalyst
superparamagnetism
title Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles
title_full Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles
title_fullStr Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles
title_full_unstemmed Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles
title_short Efficient One-Pot Synthesis of 1,4-Dihydropyridines Catalyzed by Magnetic MnFe2O4 Nanoparticles
title_sort efficient one pot synthesis of 1 4 dihydropyridines catalyzed by magnetic mnfe2o4 nanoparticles
topic 1,4-dihydropyridine
mnfe2o4
nanoparticles
catalyst
superparamagnetism
url https://journals.matheo.si/index.php/ACSi/article/view/7238
work_keys_str_mv AT somayehmoradi efficientonepotsynthesisof14dihydropyridinescatalyzedbymagneticmnfe2o4nanoparticles
AT mohsenmoradian efficientonepotsynthesisof14dihydropyridinescatalyzedbymagneticmnfe2o4nanoparticles
AT hosseinnaeimi efficientonepotsynthesisof14dihydropyridinescatalyzedbymagneticmnfe2o4nanoparticles