Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex.
The evolutionary expansion of the neocortex in mammals has been linked to enlargement of the subventricular zone (SVZ) and increased proliferative capacity of basal progenitors (BPs), notably basal radial glia (bRG). The transcription factor Pax6 is known to be highly expressed in primate, but not m...
Main Authors: | Fong Kuan Wong, Ji-Feng Fei, Felipe Mora-Bermúdez, Elena Taverna, Christiane Haffner, Jun Fu, Konstantinos Anastassiadis, A Francis Stewart, Wieland B Huttner |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-08-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.1002217 |
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