Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion
Objective The relationship between bone graft technique and postoperative outcomes for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) has not been well-defined. This study aims to determine the effect of iliac crest bone grafting (ICBG) on patient-reported outcomes (PROs) and c...
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| Format: | Article |
| Language: | English |
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Korean Spinal Neurosurgery Society
2019-12-01
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| Series: | Neurospine |
| Subjects: | |
| Online Access: | http://www.e-neurospine.org/upload/pdf/ns-1938006-003.pdf |
| _version_ | 1797334903570825216 |
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| author | Brittany E. Haws Benjamin Khechen Dil V. Patel Joon S. Yoo Jordan A. Guntin Kaitlyn L. Cardinal Junyoung Ahn Kern Singh |
| author_facet | Brittany E. Haws Benjamin Khechen Dil V. Patel Joon S. Yoo Jordan A. Guntin Kaitlyn L. Cardinal Junyoung Ahn Kern Singh |
| author_sort | Brittany E. Haws |
| collection | DOAJ |
| description | Objective The relationship between bone graft technique and postoperative outcomes for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) has not been well-defined. This study aims to determine the effect of iliac crest bone grafting (ICBG) on patient-reported outcomes (PROs) and complication rates following MIS TLIF. Methods Primary, single-level MIS TLIF patients were consecutively analyzed. Patients that prospectively received a percutaneous technique of ICBG were compared to patients that retrospectively received bone morphogenetic protein-2 (BMP-2). Complication rates were assessed perioperatively and up to 1 year postoperatively. Changes in Oswestry Disability Index (ODI), visual analogue scale (VAS) back, and VAS leg pain were compared. Rates of minimum clinically important difference (MCID) achievement at final follow-up for ODI, VAS back, and VAS leg scores were compared. Results One hundred forty-nine patients were included: 101 in the BMP-2 cohort and 48 in the ICBG cohort. The ICBG cohort demonstrated increases in intraoperative blood loss and shorter lengths of stay. ICBG patients also experienced longer operative times, though this did not reach statistical significance. No significant differences in complication or reoperation rates were identified. The ICBG cohort demonstrated greater improvements in VAS leg pain at 6-week and 12-week follow-up. No other significant differences in PROs or MCID achievement rates were identified. Conclusion Patients undergoing MIS TLIF with ICBG experienced clinically insignificant increases in intraoperative blood loss and did not experience increases in postoperative pain or disability. Complication and reoperation rates were similar between groups. These results suggest that ICBG is a safe option for MIS TLIF. |
| first_indexed | 2024-03-08T08:29:00Z |
| format | Article |
| id | doaj.art-fd2dec82e79742b9879826652d2324bc |
| institution | Directory Open Access Journal |
| issn | 2586-6583 2586-6591 |
| language | English |
| last_indexed | 2024-03-08T08:29:00Z |
| publishDate | 2019-12-01 |
| publisher | Korean Spinal Neurosurgery Society |
| record_format | Article |
| series | Neurospine |
| spelling | doaj.art-fd2dec82e79742b9879826652d2324bc2024-02-02T04:09:08ZengKorean Spinal Neurosurgery SocietyNeurospine2586-65832586-65912019-12-0116477277910.14245/ns.1938006.003895Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody FusionBrittany E. Haws0Benjamin Khechen1Dil V. Patel2Joon S. Yoo3Jordan A. Guntin4Kaitlyn L. Cardinal5Junyoung Ahn6Kern Singh Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USAObjective The relationship between bone graft technique and postoperative outcomes for minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) has not been well-defined. This study aims to determine the effect of iliac crest bone grafting (ICBG) on patient-reported outcomes (PROs) and complication rates following MIS TLIF. Methods Primary, single-level MIS TLIF patients were consecutively analyzed. Patients that prospectively received a percutaneous technique of ICBG were compared to patients that retrospectively received bone morphogenetic protein-2 (BMP-2). Complication rates were assessed perioperatively and up to 1 year postoperatively. Changes in Oswestry Disability Index (ODI), visual analogue scale (VAS) back, and VAS leg pain were compared. Rates of minimum clinically important difference (MCID) achievement at final follow-up for ODI, VAS back, and VAS leg scores were compared. Results One hundred forty-nine patients were included: 101 in the BMP-2 cohort and 48 in the ICBG cohort. The ICBG cohort demonstrated increases in intraoperative blood loss and shorter lengths of stay. ICBG patients also experienced longer operative times, though this did not reach statistical significance. No significant differences in complication or reoperation rates were identified. The ICBG cohort demonstrated greater improvements in VAS leg pain at 6-week and 12-week follow-up. No other significant differences in PROs or MCID achievement rates were identified. Conclusion Patients undergoing MIS TLIF with ICBG experienced clinically insignificant increases in intraoperative blood loss and did not experience increases in postoperative pain or disability. Complication and reoperation rates were similar between groups. These results suggest that ICBG is a safe option for MIS TLIF.http://www.e-neurospine.org/upload/pdf/ns-1938006-003.pdfminimally invasive transforaminal lumbar interbody fusioniliac crest bone graftbone morphogenic protein-2oswestry disability indexvisual analogue scaleminimum clinically important difference |
| spellingShingle | Brittany E. Haws Benjamin Khechen Dil V. Patel Joon S. Yoo Jordan A. Guntin Kaitlyn L. Cardinal Junyoung Ahn Kern Singh Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion Neurospine minimally invasive transforaminal lumbar interbody fusion iliac crest bone graft bone morphogenic protein-2 oswestry disability index visual analogue scale minimum clinically important difference |
| title | Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion |
| title_full | Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion |
| title_fullStr | Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion |
| title_full_unstemmed | Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion |
| title_short | Impact of Iliac Crest Bone Grafting on Postoperative Outcomes and Complication Rates Following Minimally Invasive Transforaminal Lumbar Interbody Fusion |
| title_sort | impact of iliac crest bone grafting on postoperative outcomes and complication rates following minimally invasive transforaminal lumbar interbody fusion |
| topic | minimally invasive transforaminal lumbar interbody fusion iliac crest bone graft bone morphogenic protein-2 oswestry disability index visual analogue scale minimum clinically important difference |
| url | http://www.e-neurospine.org/upload/pdf/ns-1938006-003.pdf |
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