Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers

Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers

Abstract Background In breast cancer, as in all cancers, genetic and epigenetic deregulations can result in out-of-context expressions of a set of normally silent tissue-specific genes. The activation of some of these genes in various cancers empowers tumours cells with new properties and drives enh...

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Bibliographic Details
Main Authors: Emmanuelle Jacquet, Florent Chuffart, Anne-Laure Vitte, Eleni Nika, Mireille Mousseau, Saadi Khochbin, Sophie Rousseaux, Ekaterina Bourova-Flin
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Genomics
Subjects:
Cancer/testis antigens
Breast cancer
Ectopic expression
Survival analysis
Prognosis biomarkers
Online Access:https://doi.org/10.1186/s12864-023-09571-3

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