Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report
In the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed inc...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/5/1044 |
| _version_ | 1797598131016171520 |
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| author | Ivana Papežíková Veronika Piačková Iva Dyková Ali Asghar Baloch Hana Kocour Kroupová Eliška Zusková Ľubomír Pojezdal Hana Minářová Eva Syrová Hana Banďouchová Pavel Hyršl Kateřina Matějíčková Jiří Pikula Miroslava Palíková |
| author_facet | Ivana Papežíková Veronika Piačková Iva Dyková Ali Asghar Baloch Hana Kocour Kroupová Eliška Zusková Ľubomír Pojezdal Hana Minářová Eva Syrová Hana Banďouchová Pavel Hyršl Kateřina Matějíčková Jiří Pikula Miroslava Palíková |
| author_sort | Ivana Papežíková |
| collection | DOAJ |
| description | In the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed increased monocyte and decreased lymphocyte counts in CEV-affected fish compared to healthy control fish. Regarding immune system functioning, the present work shows, for the first time, enhanced phagocytic activity in CEV-affected fish. Respiratory burst of phagocytes was strongly increased in diseased fish, the increase being attributed to an increased phagocyte count rather than enhancement of their metabolic activity. The present work also newly shows histopathological changes in the pancreatic tissue of diseased koi. |
| first_indexed | 2024-03-11T03:15:00Z |
| format | Article |
| id | doaj.art-fd2ec7da87eb4467898cfd043af5a753 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-11T03:15:00Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-fd2ec7da87eb4467898cfd043af5a7532023-11-18T03:38:08ZengMDPI AGViruses1999-49152023-04-01155104410.3390/v15051044Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case ReportIvana Papežíková0Veronika Piačková1Iva Dyková2Ali Asghar Baloch3Hana Kocour Kroupová4Eliška Zusková5Ľubomír Pojezdal6Hana Minářová7Eva Syrová8Hana Banďouchová9Pavel Hyršl10Kateřina Matějíčková11Jiří Pikula12Miroslava Palíková13Department of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech RepublicUniversity of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech RepublicDepartment of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech RepublicUniversity of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech RepublicUniversity of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech RepublicUniversity of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Centre of Aquaculture and Biodiversity of Hydrocenoses, Zátiší 728/II, 389 25 Vodňany, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute Brno, 621 00 Brno-Medlánky, Czech RepublicDepartment of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech RepublicDepartment of Ecology and Diseases of Zoo Animals, Game, Fish and Bees, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno, Palackého tř. 1946/1, 612 42 Brno, Czech RepublicDepartment of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech RepublicDepartment of Experimental Biology, Masaryk University, 625 00 Brno, Czech RepublicDepartment of Infectious Diseases and Preventive Medicine, Veterinary Research Institute Brno, 621 00 Brno-Medlánky, Czech RepublicDepartment of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech RepublicDepartment of Zoology, Fisheries, Hydrobiology and Apiculture, Mendel University in Brno, 613 00 Brno, Czech RepublicIn the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed increased monocyte and decreased lymphocyte counts in CEV-affected fish compared to healthy control fish. Regarding immune system functioning, the present work shows, for the first time, enhanced phagocytic activity in CEV-affected fish. Respiratory burst of phagocytes was strongly increased in diseased fish, the increase being attributed to an increased phagocyte count rather than enhancement of their metabolic activity. The present work also newly shows histopathological changes in the pancreatic tissue of diseased koi.https://www.mdpi.com/1999-4915/15/5/1044koi sleepy diseaseimmunologyrespiratory bursthistology |
| spellingShingle | Ivana Papežíková Veronika Piačková Iva Dyková Ali Asghar Baloch Hana Kocour Kroupová Eliška Zusková Ľubomír Pojezdal Hana Minářová Eva Syrová Hana Banďouchová Pavel Hyršl Kateřina Matějíčková Jiří Pikula Miroslava Palíková Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report Viruses koi sleepy disease immunology respiratory burst histology |
| title | Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report |
| title_full | Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report |
| title_fullStr | Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report |
| title_full_unstemmed | Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report |
| title_short | Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report |
| title_sort | clinical and laboratory parameters of carp edema virus disease a case report |
| topic | koi sleepy disease immunology respiratory burst histology |
| url | https://www.mdpi.com/1999-4915/15/5/1044 |
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