Postbiotics in Human Health: A Narrative Review
In the 21st century, compressive health and functional foods are advocated by increasingly more people in order to eliminate sub-health conditions. Probiotics and postbiotics have gradually become the focus of scientific and nutrition communities. With the maturity and wide application of probiotics...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/15/2/291 |
| _version_ | 1797438155114151936 |
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| author | Linxi Ma Huaijun Tu Tingtao Chen |
| author_facet | Linxi Ma Huaijun Tu Tingtao Chen |
| author_sort | Linxi Ma |
| collection | DOAJ |
| description | In the 21st century, compressive health and functional foods are advocated by increasingly more people in order to eliminate sub-health conditions. Probiotics and postbiotics have gradually become the focus of scientific and nutrition communities. With the maturity and wide application of probiotics, the safety concerns and other disadvantages are non-negligible as we review here. As new-era products, postbiotics continue to have considerable potential as well as plentiful drawbacks to optimize. “Postbiotic” has been defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Here, the evolution of the concept “postbiotics” is reviewed. The underlying mechanisms of postbiotic action are discussed. Current insight suggests that postbiotics exert efficacy through protective modulation, fortifying the epithelial barrier and modulation of immune responses. Finally, we provide an overview of the comparative advantages and the current application in the food industry at pharmaceutical and biomedical levels. |
| first_indexed | 2024-03-09T11:32:11Z |
| format | Article |
| id | doaj.art-fd363b557cff41e7948919073f5a0b6c |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T11:32:11Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-fd363b557cff41e7948919073f5a0b6c2023-11-30T23:49:32ZengMDPI AGNutrients2072-66432023-01-0115229110.3390/nu15020291Postbiotics in Human Health: A Narrative ReviewLinxi Ma0Huaijun Tu1Tingtao Chen2Departments of Geriatrics, The Second Affiliated Hospital of Nanchang University, Nanchang 330031, ChinaDepartments of Geriatrics, The Second Affiliated Hospital of Nanchang University, Nanchang 330031, ChinaDepartments of Geriatrics, The Second Affiliated Hospital of Nanchang University, Nanchang 330031, ChinaIn the 21st century, compressive health and functional foods are advocated by increasingly more people in order to eliminate sub-health conditions. Probiotics and postbiotics have gradually become the focus of scientific and nutrition communities. With the maturity and wide application of probiotics, the safety concerns and other disadvantages are non-negligible as we review here. As new-era products, postbiotics continue to have considerable potential as well as plentiful drawbacks to optimize. “Postbiotic” has been defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Here, the evolution of the concept “postbiotics” is reviewed. The underlying mechanisms of postbiotic action are discussed. Current insight suggests that postbiotics exert efficacy through protective modulation, fortifying the epithelial barrier and modulation of immune responses. Finally, we provide an overview of the comparative advantages and the current application in the food industry at pharmaceutical and biomedical levels.https://www.mdpi.com/2072-6643/15/2/291postbioticsprobioticscomprehensive healthimmunomodulation |
| spellingShingle | Linxi Ma Huaijun Tu Tingtao Chen Postbiotics in Human Health: A Narrative Review Nutrients postbiotics probiotics comprehensive health immunomodulation |
| title | Postbiotics in Human Health: A Narrative Review |
| title_full | Postbiotics in Human Health: A Narrative Review |
| title_fullStr | Postbiotics in Human Health: A Narrative Review |
| title_full_unstemmed | Postbiotics in Human Health: A Narrative Review |
| title_short | Postbiotics in Human Health: A Narrative Review |
| title_sort | postbiotics in human health a narrative review |
| topic | postbiotics probiotics comprehensive health immunomodulation |
| url | https://www.mdpi.com/2072-6643/15/2/291 |
| work_keys_str_mv | AT linxima postbioticsinhumanhealthanarrativereview AT huaijuntu postbioticsinhumanhealthanarrativereview AT tingtaochen postbioticsinhumanhealthanarrativereview |