Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2020-07-01
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| Series: | ACS Central Science |
| Online Access: | https://doi.org/10.1021/acscentsci.0c00411 |
| _version_ | 1818402886999080960 |
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| author | Michael J. Bond Ling Chu Dhanusha A. Nalawansha Ke Li Craig M. Crews |
| author_facet | Michael J. Bond Ling Chu Dhanusha A. Nalawansha Ke Li Craig M. Crews |
| author_sort | Michael J. Bond |
| collection | DOAJ |
| first_indexed | 2024-12-14T08:15:30Z |
| format | Article |
| id | doaj.art-fd36cde10c1e43fbb63ded6891baa8a3 |
| institution | Directory Open Access Journal |
| issn | 2374-7951 |
| language | English |
| last_indexed | 2024-12-14T08:15:30Z |
| publishDate | 2020-07-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Central Science |
| spelling | doaj.art-fd36cde10c1e43fbb63ded6891baa8a32022-12-21T23:09:56ZengAmerican Chemical SocietyACS Central Science2374-79512020-07-01681367137510.1021/acscentsci.0c00411Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACsMichael J. Bond0Ling Chu1Dhanusha A. Nalawansha2Ke Li3Craig M. Crews4Department of Pharmacology, Yale University, New Haven, Connecticut, United StatesDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United StatesDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United StatesDepartment of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United StatesDepartment of Pharmacology, Yale University, New Haven, Connecticut, United Stateshttps://doi.org/10.1021/acscentsci.0c00411 |
| spellingShingle | Michael J. Bond Ling Chu Dhanusha A. Nalawansha Ke Li Craig M. Crews Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs ACS Central Science |
| title | Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs |
| title_full | Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs |
| title_fullStr | Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs |
| title_full_unstemmed | Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs |
| title_short | Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs |
| title_sort | targeted degradation of oncogenic krasg12c by vhl recruiting protacs |
| url | https://doi.org/10.1021/acscentsci.0c00411 |
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