DNA methylation in blood as a mediator of the association of mid-childhood body mass index with cardio-metabolic risk score in early adolescence

DNA methylation in blood as a mediator of the association of mid-childhood body mass index with cardio-metabolic risk score in early adolescence

Obesity is associated with higher cardio-metabolic risk even in childhood and adolescence; whether this association is mediated by epigenetic mechanisms remains unclear. We examined the extent to which mid-childhood body mass index (BMI) z-score (median age 7.7 years) was associated with cardio-meta...

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Bibliographic Details
Main Authors: Jian V. Huang, Andres Cardenas, Elena Colicino, C. Mary Schooling, Sheryl L. Rifas-Shiman, Golareh Agha, Yinan Zheng, Lifang Hou, Allan C. Just, Augusto A. Litonjua, Dawn L. DeMeo, Xihong Lin, Emily Oken, Marie-France Hivert, Andrea A. Baccarelli
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Epigenetics
Subjects:
obesity
bmi
cardio-metabolic
dna methylation
epigenetics
mediation
Online Access:http://dx.doi.org/10.1080/15592294.2018.1543503

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