Biological functions of epicatechin: Plant cell to human cell health
Research on epicatechin as a potential nutraceutical has gained huge interest due to its critical biological functions and ease of availability. Several in vitro and in vivo studies have been carried out to explore its therapeutic potential and have shown excellent biological effects. In spite of it...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-01-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464618305395 |
| _version_ | 1818596366429978624 |
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| author | Monika Prakash B.V. Basavaraj K.N. Chidambara Murthy |
| author_facet | Monika Prakash B.V. Basavaraj K.N. Chidambara Murthy |
| author_sort | Monika Prakash |
| collection | DOAJ |
| description | Research on epicatechin as a potential nutraceutical has gained huge interest due to its critical biological functions and ease of availability. Several in vitro and in vivo studies have been carried out to explore its therapeutic potential and have shown excellent biological effects. In spite of its wide range of biological activity, poor bioavailability and instability in in vivo system have limited its application. One of our studies on nanoformulation of catechin rich extract suggested enhanced antioxidant activity and in vitro bioavailability. In this review, we have provided information on the discovery of epicatechin in plants and its role in the protection of plant. Additionally, information on the biological activities of epicatechin in animals and human is discussed. Article also showcases factors that influence pharmacokinetics and bioavailability of epicatechin. An ample coverage on the scope and applications of nanotechnology in the bioavailability enhancement and biological effects are duly emphasized. |
| first_indexed | 2024-12-16T11:30:46Z |
| format | Article |
| id | doaj.art-fd40cc9a8d82474881daf9e85643d658 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-16T11:30:46Z |
| publishDate | 2019-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-fd40cc9a8d82474881daf9e85643d6582022-12-21T22:33:15ZengElsevierJournal of Functional Foods1756-46462019-01-01521424Biological functions of epicatechin: Plant cell to human cell healthMonika Prakash0B.V. Basavaraj1K.N. Chidambara Murthy2Department of Biotechnology, Ramaiah Institute of Technology, MSR Nagar, MSRIT Post, Bengaluru 560 054, IndiaDepartment of Pharmaceutics, Faculty of Pharmacy, Ramaiah University of Applied Sciences, MSR Nagar, MSRIT Post, Bengaluru 560 054, IndiaCentral Research Laboratory, Ramaiah Medical College & Hospitals, MSR Nagar, MSRIT Post, Bengaluru 560 054, India; Corresponding author.Research on epicatechin as a potential nutraceutical has gained huge interest due to its critical biological functions and ease of availability. Several in vitro and in vivo studies have been carried out to explore its therapeutic potential and have shown excellent biological effects. In spite of its wide range of biological activity, poor bioavailability and instability in in vivo system have limited its application. One of our studies on nanoformulation of catechin rich extract suggested enhanced antioxidant activity and in vitro bioavailability. In this review, we have provided information on the discovery of epicatechin in plants and its role in the protection of plant. Additionally, information on the biological activities of epicatechin in animals and human is discussed. Article also showcases factors that influence pharmacokinetics and bioavailability of epicatechin. An ample coverage on the scope and applications of nanotechnology in the bioavailability enhancement and biological effects are duly emphasized.http://www.sciencedirect.com/science/article/pii/S1756464618305395BioavailabilityBiological functionsEpicatechinNanotechnologyPharmacokinetics |
| spellingShingle | Monika Prakash B.V. Basavaraj K.N. Chidambara Murthy Biological functions of epicatechin: Plant cell to human cell health Journal of Functional Foods Bioavailability Biological functions Epicatechin Nanotechnology Pharmacokinetics |
| title | Biological functions of epicatechin: Plant cell to human cell health |
| title_full | Biological functions of epicatechin: Plant cell to human cell health |
| title_fullStr | Biological functions of epicatechin: Plant cell to human cell health |
| title_full_unstemmed | Biological functions of epicatechin: Plant cell to human cell health |
| title_short | Biological functions of epicatechin: Plant cell to human cell health |
| title_sort | biological functions of epicatechin plant cell to human cell health |
| topic | Bioavailability Biological functions Epicatechin Nanotechnology Pharmacokinetics |
| url | http://www.sciencedirect.com/science/article/pii/S1756464618305395 |
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