HLA diversity in ethnic populations can affect detection of donor-specific antibodies by single antigen beads

HLA diversity in ethnic populations can affect detection of donor-specific antibodies by single antigen beads

IntroductionIn solid-organ transplantation, human leukocyte antigen (HLA) donor-specific antibodies (DSA) are strongly associated with graft rejection, graft loss, and patient death. The predominant tests used for detecting HLA DSA before and after solid-organ transplantation are HLA single antigen...

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Bibliographic Details
Main Authors: Justin C. Quon, Kelli Kaneta, Nicholas Fotiadis, Jondavid Menteer, Rachel M. Lestz, Molly Weisert, Lee Ann Baxter-Lowe
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
donor specific antibodies
HLA antibodies
HLA diversity
race and ethnicity
single antigen bead assays (SAB)
solid organ transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287028/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287028/full

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