Restoring Axonal Organelle Motility and Regeneration in Cultured FUS-ALS Motoneurons through Magnetic Field Stimulation Suggests an Alternative Therapeutic Approach

Restoring Axonal Organelle Motility and Regeneration in Cultured FUS-ALS Motoneurons through Magnetic Field Stimulation Suggests an Alternative Therapeutic Approach

Amyotrophic lateral sclerosis (ALS) is a devastating motoneuron disease characterized by sustained loss of neuromuscular junctions, degenerating corticospinal motoneurons and rapidly progressing muscle paralysis. Motoneurons have unique features, essentially a highly polarized, lengthy architecture...

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Bibliographic Details
Main Authors: Wonphorn Kandhavivorn, Hannes Glaß, Thomas Herrmannsdörfer, Tobias M. Böckers, Marc Uhlarz, Jonas Gronemann, Richard H. W. Funk, Jens Pietzsch, Arun Pal, Andreas Hermann
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cells
Subjects:
amyotrophic lateral sclerosis
induced pluripotent stem cells
AC electromagnetic stimulation
axonopathy
axonal organelle trafficking
axonal sprouting
Online Access:https://www.mdpi.com/2073-4409/12/11/1502

Internet

https://www.mdpi.com/2073-4409/12/11/1502

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