Effect of a New Substance with Pyridoindole Structure on Adult Neurogenesis, Shape of Neurons, and Behavioral Outcomes in a Chronic Mild Stress Model in Rats
Despite an accumulating number of studies, treatments for depression are currently insufficient. Therefore, the search for new substances with antidepressant potential is very important. In this study, we hypothesized that treatment with a newly synthesized pyridoindole derivative compound SMe1EC2M3...
Main Authors: | Alexandra Zvozilova, Alexandra Reichova, Mojmir Mach, Jan Bakos, Romana Koprdova |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-01-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/25/2/845 |
Similar Items
-
Antidepressants with antimicrobial activity? A promising therapeutic strategy
by: Gloria M. González, et al.
Published: (2022-07-01) -
The effect of triple reuptake inhibitor toludesvenlafaxine on neurological function in cerebral ischemic rats
by: Xiaohui Sun, et al.
Published: (2023-04-01) -
Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
by: Lucia Kovacikova, et al.
Published: (2021-05-01) -
Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder
by: Azmeraw T. Amare, et al.
Published: (2018-03-01) -
Escitalopram versus other antidepressive agents for major depressive disorder: a systematic review and meta-analysis
by: Juntao Yin, et al.
Published: (2023-11-01)