Epigenetic Mediation of <i>AKT1</i> rs1130233’s Effect on Delta-9-Tetrahydrocannabinol-Induced Medial Temporal Function during Fear Processing

Epigenetic Mediation of <i>AKT1</i> rs1130233’s Effect on Delta-9-Tetrahydrocannabinol-Induced Medial Temporal Function during Fear Processing

High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally, THC effects have been shown to be modulated by genotype, including the single nucleotide polymorphism (SNP) rs1130233 at the protein kinase <i&g...

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Bibliographic Details
Main Authors: Grace Blest-Hopley, Marco Colizzi, Diana Prata, Vincent Giampietro, Michael Brammer, Philip McGuire, Sagnik Bhattacharyya
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Brain Sciences
Subjects:
THC
cannabis
Marijuana
<i>AKT1</i>
Epigenetics
fMRI
Online Access:https://www.mdpi.com/2076-3425/11/9/1240

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