HOP, a Co-chaperone Involved in Response to Stress in Plants
Protein folding is an essential step for protein functionality. In eukaryotes this process is carried out by multiple chaperones that act in a cooperative manner to maintain the proteome homeostasis. Some of these chaperones are assisted during protein folding by different co-chaperones. One of thes...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-10-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2020.591940/full |
| _version_ | 1818112170191224832 |
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| author | René Toribio Silvina Mangano Nuria Fernández-Bautista Alfonso Muñoz M. Mar Castellano |
| author_facet | René Toribio Silvina Mangano Nuria Fernández-Bautista Alfonso Muñoz M. Mar Castellano |
| author_sort | René Toribio |
| collection | DOAJ |
| description | Protein folding is an essential step for protein functionality. In eukaryotes this process is carried out by multiple chaperones that act in a cooperative manner to maintain the proteome homeostasis. Some of these chaperones are assisted during protein folding by different co-chaperones. One of these co-chaperones is HOP, the HSP70-HSP90 organizing protein. This assistant protein, due to its importance, has been deeply analyzed in other eukaryotes, but its function has only recently started to be envisaged in plants. In this kingdom, the role of HOP has been associated to plant response to different cellular, biotic and abiotic stresses. In this article, we analyze the current knowledge about HOP in eukaryotes, paying a special attention to the recently described roles of HOP in plants. In addition, we discuss the recent breakthroughs in the field and the possible new avenues for the study of plant HOP proteins in the future. |
| first_indexed | 2024-12-11T03:14:41Z |
| format | Article |
| id | doaj.art-fd478102ef574c8a84c4ea9ee9742c8f |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-11T03:14:41Z |
| publishDate | 2020-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-fd478102ef574c8a84c4ea9ee9742c8f2022-12-22T01:22:48ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2020-10-011110.3389/fpls.2020.591940591940HOP, a Co-chaperone Involved in Response to Stress in PlantsRené Toribio0Silvina Mangano1Nuria Fernández-Bautista2Alfonso Muñoz3M. Mar Castellano4Centro de Biotecnología y Genómica de Plantas, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Universidad Politécnica de Madrid (UPM), Madrid, SpainCentro de Biotecnología y Genómica de Plantas, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Universidad Politécnica de Madrid (UPM), Madrid, SpainCentro de Biotecnología y Genómica de Plantas, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Universidad Politécnica de Madrid (UPM), Madrid, SpainDepartamento de Botánica, Ecología y Fisiología Vegetal, Universidad de Córdoba, Córdoba, SpainCentro de Biotecnología y Genómica de Plantas, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Universidad Politécnica de Madrid (UPM), Madrid, SpainProtein folding is an essential step for protein functionality. In eukaryotes this process is carried out by multiple chaperones that act in a cooperative manner to maintain the proteome homeostasis. Some of these chaperones are assisted during protein folding by different co-chaperones. One of these co-chaperones is HOP, the HSP70-HSP90 organizing protein. This assistant protein, due to its importance, has been deeply analyzed in other eukaryotes, but its function has only recently started to be envisaged in plants. In this kingdom, the role of HOP has been associated to plant response to different cellular, biotic and abiotic stresses. In this article, we analyze the current knowledge about HOP in eukaryotes, paying a special attention to the recently described roles of HOP in plants. In addition, we discuss the recent breakthroughs in the field and the possible new avenues for the study of plant HOP proteins in the future.https://www.frontiersin.org/articles/10.3389/fpls.2020.591940/fullHOPHSP70HSP90co-chaperoneprotein foldingquality control |
| spellingShingle | René Toribio Silvina Mangano Nuria Fernández-Bautista Alfonso Muñoz M. Mar Castellano HOP, a Co-chaperone Involved in Response to Stress in Plants Frontiers in Plant Science HOP HSP70 HSP90 co-chaperone protein folding quality control |
| title | HOP, a Co-chaperone Involved in Response to Stress in Plants |
| title_full | HOP, a Co-chaperone Involved in Response to Stress in Plants |
| title_fullStr | HOP, a Co-chaperone Involved in Response to Stress in Plants |
| title_full_unstemmed | HOP, a Co-chaperone Involved in Response to Stress in Plants |
| title_short | HOP, a Co-chaperone Involved in Response to Stress in Plants |
| title_sort | hop a co chaperone involved in response to stress in plants |
| topic | HOP HSP70 HSP90 co-chaperone protein folding quality control |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2020.591940/full |
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