Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release.

Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release.

Hepatitis C virus (HCV) causes acute hepatitis C and can lead to life-threatening complications if it becomes chronic. The HCV genome is a single plus strand of RNA. Its intracellular replication is a spatiotemporally coordinated process of RNA translation upon cell infection, RNA synthesis within a...

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Bibliographic Details
Main Authors:	Carolin Zitzmann, Lars Kaderali, Alan S Perelson
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-11-01
Series:	PLoS Computational Biology
Online Access:	https://doi.org/10.1371/journal.pcbi.1008421

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