Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide

Identification of autoantibodies in human plasma recognizing an apoB-100 LDL receptor binding site peptide

The aim of this study was to test the hypothesis that autoantibodies recognize amino acid sequences in the LDL receptor binding region of apolipoprotein B-100 (apoB-100). Autoantibodies against an unmodified or malondialdehyde (MDA)-modified LDL receptor binding site peptide were determined by ELISA...

Full description

Bibliographic Details
Main Authors:	Gunilla Nordin Fredrikson, Göran Berglund, Ragnar Alm, Jan-Åke Nilsson, Prediman K. Shah, Jan Nilsson
Format:	Article
Language:	English
Published:	Elsevier 2006-09-01
Series:	Journal of Lipid Research
Subjects:	apolipoprotein B-100 atherosclerosis low density lipoprotein
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520434728

Similar Items

LDL phospholipid hydrolysis produces modified electronegative particles with an unfolded apoB-100 protein
by: Liana Asatryan, et al.
Published: (2005-01-01)

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans
by: Berthil H.C.M.T. Prinsen, et al.
Published: (2003-07-01)

The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles
by: Christina Christoffersen, et al.
Published: (2012-10-01)

Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice[S]
by: Adam E. Mullick, et al.
Published: (2011-05-01)

Relación entre tipo y cantidad de carbohidratos dietarios con el perfil lipídico y ApoB100 en adultos
by: Martha Guerra, et al.
Published: (2010-08-01)

Metabolism of apoB lipoproteins of intestinal and hepatic origin during constant feeding of small amounts of fat
by: Chunyu Zheng, et al.
Published: (2006-08-01)

Epigallocatechin gallate increases the formation of cytosolic lipid droplets and decreases the secretion of apoB-100 VLDL
by: Lu Li, et al.
Published: (2006-01-01)

2D-NMR reveals different populations of exposed lysine residues in the apoB-100 protein of electronegative and electropositive fractions of LDL particles[S]
by: Francisco J. Blanco, et al.
Published: (2010-06-01)

The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatins⃞
by: Dawn E. Telford, et al.
Published: (2007-03-01)

Oxidative events cause degradation of apoB-100 but not of apo[a] and facilitate enzymatic cleavage of both proteins
by: Celina Edelstein, et al.
Published: (2001-10-01)

Conformational changes of apoB-100 in SMase-modified LDL mediate formation of large aggregates at acidic pH[S]
by: Mia Sneck, et al.
Published: (2012-09-01)

Increased production of VLDL apoB-100 in subjects with familial hypercholesterolemia carrying the same null LDL receptor gene mutation
by: André J. Tremblay, et al.
Published: (2004-05-01)

Abnormal in vivo metabolism of apoB-containing lipoproteins in human apoE deficiency
by: Katsunori Ikewaki, et al.
Published: (2004-07-01)

Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway[S]
by: Eric A. Fisher, et al.
Published: (2011-06-01)

Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor
by: Danijela Lucic, et al.
Published: (2007-02-01)

ApoA-IV modulates the secretory trafficking of apoB and the size of triglyceride-rich lipoproteins
by: Richard B. Weinberg, et al.
Published: (2012-04-01)

Immuno-electron cryo-microscopy imaging reveals a looped topology of apoB at the surface of human LDL[S]
by: Yuhang Liu, et al.
Published: (2011-06-01)

The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA2
by: Constantinos C. Tellis, et al.
Published: (2013-12-01)

Biphasic Production of Anti-ApoB100 Autoantibodies in Obese Humans and Mice
by: Moon Kyung Choe, et al.
Published: (2021-04-01)

The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient “apoB-48-only” and “apoB-100-only” mice
by: Helén L. Dichek, et al.
Published: (2004-03-01)

Hepatic secretion of small lipoprotein particles in apobec-1−/− mice is regulated by the LDL receptor
by: Fatiha Nassir, et al.
Published: (2004-09-01)

Rapid turnover of apolipoprotein C-III-containing triglyceride-rich lipoproteins contributing to the formation of LDL subfractionss⃞
by: Zheng Chunyu, et al.
Published: (2007-05-01)

Immunochemical evidence that human apoB differs when expressed in rodent versus human cells
by: Xingyu Wang, et al.
Published: (2003-03-01)

Discordantly normal ApoB relative to elevated LDL-C in persons with metabolic disorders: A marker of atherogenic heterogeneity
by: Alexander C. Razavi, et al.
Published: (2021-09-01)

Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells
by: Florent Lalanne, et al.
Published: (2005-06-01)

ApoB-containing lipoproteins in apoE-deficient mice are not metabolized by the class B scavenger receptor BI
by: Nancy R. Webb, et al.
Published: (2004-02-01)

Secretion of apoB- and apoA-I-containing lipoproteins by chick kidney
by: Patrizia Tarugi, et al.
Published: (1998-04-01)

ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins
by: Ryan E. Temel, et al.
Published: (2007-07-01)

ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan
by: Katherine Olin-Lewis, et al.
Published: (2002-11-01)

Utility of non-HDL-C and apoB targets in the context of new more aggressive lipid guidelines
by: Renato Quispe, et al.
Published: (2021-09-01)

Integral apolipoproteins increase surface-located triacylglycerol in intact native apoB-100-containing lipoproteins
by: Elizabeth Boyle-Roden, et al.
Published: (2005-08-01)

Apolipoprotein A-I mimetic peptide 4F blocks sphingomyelinase-induced LDL aggregation
by: Su Duy Nguyen, et al.
Published: (2015-06-01)

A Novel Variant in APOB Gene Causes Extremely Low LDL-C Without Known Adverse Effects
by: Ida Surakka, PhD, et al.
Published: (2020-05-01)

Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice
by: Nancy R. Webb, et al.
Published: (2002-09-01)

ApoE genotype affects allele-specific apo[a] levels for large apo[a] sizes in African Americans: the Harlem-Basset Studys⃞
by: Erdembileg Anuurad, et al.
Published: (2007-03-01)

Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2
by: Pia Stillemark-Billton, et al.
Published: (2005-01-01)

Apolipoprotein[a] secretion from hepatoma cells is regulated in a size-dependent manner by alterations in disulfide bond formation
by: Fatiha Nassir, et al.
Published: (2003-04-01)

Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method
by: Grace Marie Jones, et al.
Published: (2020-03-01)

Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism
by: Margaret R. Diffenderfer, et al.
Published: (2012-06-01)

ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice
by: Myron E. Hinsdale, et al.
Published: (2002-09-01)