Carney Complex: Eleven Open Heart Operations in a Single Family
Herein, we report on a family with Carney complex. Four members of the family underwent a total of 11 open heart operations as well as 9 other operations to treat extrathoracic masses. All the family members met at least 2 major clinical criteria and 1 supplemental criterion. We analyzed their genom...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society for Thoracic and Cardiovascular Surgery
2017-12-01
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| Series: | Korean Journal of Thoracic and Cardiovascular Surgery |
| Subjects: | |
| Online Access: | http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2017.50.6.471 |
| _version_ | 1811202420803371008 |
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| author | Sung Joon Han Woosik Han Min-Woong Kang Jae Hyeon Yu Shinkwang Kang Myung Hoon Na |
| author_facet | Sung Joon Han Woosik Han Min-Woong Kang Jae Hyeon Yu Shinkwang Kang Myung Hoon Na |
| author_sort | Sung Joon Han |
| collection | DOAJ |
| description | Herein, we report on a family with Carney complex. Four members of the family underwent a total of 11 open heart operations as well as 9 other operations to treat extrathoracic masses. All the family members met at least 2 major clinical criteria and 1 supplemental criterion. We analyzed their genomic loci, including the protein kinase A regulatory subunit 1 gene. The results revealed no specific mutations, except for a com-mon single nucleotide polymorphism. This case series of Carney complex emphasizes the importance of close longitudinal follow-up because of the high rate of tumor recurrence irrespective of the site. Clinicians should not overlook the specific features of familial myxoma. |
| first_indexed | 2024-04-12T02:38:13Z |
| format | Article |
| id | doaj.art-fd58fb87f336420b9e0ef99b627fc16e |
| institution | Directory Open Access Journal |
| issn | 2233-601X 2093-6516 |
| language | English |
| last_indexed | 2024-04-12T02:38:13Z |
| publishDate | 2017-12-01 |
| publisher | Korean Society for Thoracic and Cardiovascular Surgery |
| record_format | Article |
| series | Korean Journal of Thoracic and Cardiovascular Surgery |
| spelling | doaj.art-fd58fb87f336420b9e0ef99b627fc16e2022-12-22T03:51:25ZengKorean Society for Thoracic and Cardiovascular SurgeryKorean Journal of Thoracic and Cardiovascular Surgery2233-601X2093-65162017-12-0150647147310.5090/kjtcs.2017.50.6.471Carney Complex: Eleven Open Heart Operations in a Single FamilySung Joon Han0Woosik Han1Min-Woong Kang2Jae Hyeon Yu3Shinkwang Kang4Myung Hoon Na5Chungnam National University School of MedicineChungnam National University School of MedicineChungnam National University School of MedicineChungnam National University School of MedicineChungnam National University School of MedicineChungnam National University School of MedicineHerein, we report on a family with Carney complex. Four members of the family underwent a total of 11 open heart operations as well as 9 other operations to treat extrathoracic masses. All the family members met at least 2 major clinical criteria and 1 supplemental criterion. We analyzed their genomic loci, including the protein kinase A regulatory subunit 1 gene. The results revealed no specific mutations, except for a com-mon single nucleotide polymorphism. This case series of Carney complex emphasizes the importance of close longitudinal follow-up because of the high rate of tumor recurrence irrespective of the site. Clinicians should not overlook the specific features of familial myxoma.http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2017.50.6.471Carney complexMyxomaFamilial myxoma |
| spellingShingle | Sung Joon Han Woosik Han Min-Woong Kang Jae Hyeon Yu Shinkwang Kang Myung Hoon Na Carney Complex: Eleven Open Heart Operations in a Single Family Korean Journal of Thoracic and Cardiovascular Surgery Carney complex Myxoma Familial myxoma |
| title | Carney Complex: Eleven Open Heart Operations in a Single Family |
| title_full | Carney Complex: Eleven Open Heart Operations in a Single Family |
| title_fullStr | Carney Complex: Eleven Open Heart Operations in a Single Family |
| title_full_unstemmed | Carney Complex: Eleven Open Heart Operations in a Single Family |
| title_short | Carney Complex: Eleven Open Heart Operations in a Single Family |
| title_sort | carney complex eleven open heart operations in a single family |
| topic | Carney complex Myxoma Familial myxoma |
| url | http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2017.50.6.471 |
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