AMPK Mediates Early Activation of the Unfolded Protein Response through a Positive Feedback Loop in Palmitate-Treated Muscle Cells

AMPK Mediates Early Activation of the Unfolded Protein Response through a Positive Feedback Loop in Palmitate-Treated Muscle Cells

Background: Activation of the unfolded protein response (UPR) is closely related to the pathogenesis of many metabolic disorders. Accumulating evidence also shows that UPR and metabolic signaling pathways are interdependent. The AMP-activated protein kinase (AMPK) signal pathway controls the energy...

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Bibliographic Details
Main Authors: Jing Gong, Lu Wang, Wuchen Tao, Xiangsheng Pang, Zonghan Liu, Shiming Li, Wenjiong Li, Xiaoping Chen, Peng Zhang
Format: Article
Language:English
Published: IMR Press 2023-08-01
Series:Frontiers in Bioscience-Landmark
Subjects:
palmitate
er stress
unfolded protein response
ampk
c2c12 myotube
Online Access:https://www.imrpress.com/journal/FBL/28/8/10.31083/j.fbl2808159

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