Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study
<p>Abstract</p> <p>Background</p> <p>Insufficient sleep and poor sleep quality, considered endemic in modern society, are associated with obesity, impaired glucose tolerance and diabetes. Little, however, is known about the consequences of insufficient sleep and poor sl...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-05-01
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| Series: | BMC Women's Health |
| Online Access: | http://www.biomedcentral.com/1472-6874/10/17 |
| _version_ | 1819087690760454144 |
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| author | Frederick Ihunnaya O Enquobahrie Daniel Qiu Chunfang Abetew Dejene Williams Michelle A |
| author_facet | Frederick Ihunnaya O Enquobahrie Daniel Qiu Chunfang Abetew Dejene Williams Michelle A |
| author_sort | Frederick Ihunnaya O |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Insufficient sleep and poor sleep quality, considered endemic in modern society, are associated with obesity, impaired glucose tolerance and diabetes. Little, however, is known about the consequences of insufficient sleep and poor sleep quality during pregnancy on glucose tolerance and gestational diabetes.</p> <p>Methods</p> <p>A cohort of 1,290 women was interviewed during early pregnancy. We collected information about sleep duration and snoring during early pregnancy. Results from screening and diagnostic testing for gestational diabetes mellitus (GDM) were abstracted from medical records. Generalized linear models were fitted to derive relative risk (RR) and 95% confidence intervals (95% CIs) of GDM associated with sleep duration and snoring, respectively.</p> <p>Results</p> <p>After adjusting for maternal age and race/ethnicity, GDM risk was increased among women sleeping ≤ 4 hours compared with those sleeping 9 hours per night (RR = 5.56; 95% CI 1.31-23.69). The corresponding RR for lean women (<25 kg/m<sup>2</sup>) was 3.23 (95% CI 0.34-30.41) and 9.83 (95% CI 1.12-86.32) for overweight women (≥ 25 kg/m<sup>2</sup>). Overall, snoring was associated with a 1.86-fold increased risk of GDM (RR = 1.86; 95% CI 0.88-3.94). The risk of GDM was particularly elevated among overweight women who snored. Compared with lean women who did not snore, those who were overweight and snored had a 6.9-fold increased risk of GDM (95% CI 2.87-16.6).</p> <p>Conclusions</p> <p>These preliminary findings suggest associations of short sleep duration and snoring with glucose intolerance and GDM. Though consistent with studies of men and non-pregnant women, larger studies that include objective measures of sleep duration, quality and apnea are needed to obtain more precise estimates of observed associations.</p> |
| first_indexed | 2024-12-21T21:40:09Z |
| format | Article |
| id | doaj.art-fd5a7a4ffd734090a9eb8858add2ca0f |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-12-21T21:40:09Z |
| publishDate | 2010-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-fd5a7a4ffd734090a9eb8858add2ca0f2022-12-21T18:49:22ZengBMCBMC Women's Health1472-68742010-05-011011710.1186/1472-6874-10-17Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot studyFrederick Ihunnaya OEnquobahrie DanielQiu ChunfangAbetew DejeneWilliams Michelle A<p>Abstract</p> <p>Background</p> <p>Insufficient sleep and poor sleep quality, considered endemic in modern society, are associated with obesity, impaired glucose tolerance and diabetes. Little, however, is known about the consequences of insufficient sleep and poor sleep quality during pregnancy on glucose tolerance and gestational diabetes.</p> <p>Methods</p> <p>A cohort of 1,290 women was interviewed during early pregnancy. We collected information about sleep duration and snoring during early pregnancy. Results from screening and diagnostic testing for gestational diabetes mellitus (GDM) were abstracted from medical records. Generalized linear models were fitted to derive relative risk (RR) and 95% confidence intervals (95% CIs) of GDM associated with sleep duration and snoring, respectively.</p> <p>Results</p> <p>After adjusting for maternal age and race/ethnicity, GDM risk was increased among women sleeping ≤ 4 hours compared with those sleeping 9 hours per night (RR = 5.56; 95% CI 1.31-23.69). The corresponding RR for lean women (<25 kg/m<sup>2</sup>) was 3.23 (95% CI 0.34-30.41) and 9.83 (95% CI 1.12-86.32) for overweight women (≥ 25 kg/m<sup>2</sup>). Overall, snoring was associated with a 1.86-fold increased risk of GDM (RR = 1.86; 95% CI 0.88-3.94). The risk of GDM was particularly elevated among overweight women who snored. Compared with lean women who did not snore, those who were overweight and snored had a 6.9-fold increased risk of GDM (95% CI 2.87-16.6).</p> <p>Conclusions</p> <p>These preliminary findings suggest associations of short sleep duration and snoring with glucose intolerance and GDM. Though consistent with studies of men and non-pregnant women, larger studies that include objective measures of sleep duration, quality and apnea are needed to obtain more precise estimates of observed associations.</p>http://www.biomedcentral.com/1472-6874/10/17 |
| spellingShingle | Frederick Ihunnaya O Enquobahrie Daniel Qiu Chunfang Abetew Dejene Williams Michelle A Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study BMC Women's Health |
| title | Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study |
| title_full | Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study |
| title_fullStr | Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study |
| title_full_unstemmed | Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study |
| title_short | Glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy: a pilot study |
| title_sort | glucose intolerance and gestational diabetes risk in relation to sleep duration and snoring during pregnancy a pilot study |
| url | http://www.biomedcentral.com/1472-6874/10/17 |
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