TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements.

TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements.

TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown. We now hypothesized that cytokine secretion from TREK-1-deficient AECs was regulated by cytoskel...

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Detalles Bibliográficos
Main Authors: Andreas Schwingshackl, Esra Roan, Bin Teng, Christopher M Waters
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4441361?pdf=render

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