TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements.
TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown. We now hypothesized that cytokine secretion from TREK-1-deficient AECs was regulated by cytoskel...
Autori principali: | Andreas Schwingshackl, Esra Roan, Bin Teng, Christopher M Waters |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Public Library of Science (PLoS)
2015-01-01
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Serie: | PLoS ONE |
Accesso online: | http://europepmc.org/articles/PMC4441361?pdf=render |
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