Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs
Early postnatal nutrition may have a significant subsequent impact on metabolic disorders during the entire lifespan of lambs. The aim of the present study was to describe the changes in biochemical, immunological, hepatic, and ruminal parameters of fattening lambs derived from early feed restrictio...
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MDPI AG
2018-05-01
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| Series: | Animals |
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| Online Access: | http://www.mdpi.com/2076-2615/8/6/83 |
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| author | Javier Frutos Sonia Andrés Erminio Trevisi David R. Yáñez-Ruiz Secundino López Alba Santos F. Javier Giráldez |
| author_facet | Javier Frutos Sonia Andrés Erminio Trevisi David R. Yáñez-Ruiz Secundino López Alba Santos F. Javier Giráldez |
| author_sort | Javier Frutos |
| collection | DOAJ |
| description | Early postnatal nutrition may have a significant subsequent impact on metabolic disorders during the entire lifespan of lambs. The aim of the present study was to describe the changes in biochemical, immunological, hepatic, and ruminal parameters of fattening lambs derived from early feed restriction during the suckling phase. Twenty-four merino lambs (average body weight, BW, 4.81 ± 0.256 kg) were used, 12 of them were milk-fed ad libitum (ADL) remaining permanently with their dams, whereas the other 12 lambs (restricted, RES) were subjected to milk restriction. After weaning, all the lambs were fed 35 g/kg BW per day of the same complete pelleted diet to ensure no differences between groups in dry matter intake (603 vs. 607 g/day for ADL and RES lambs, respectively, p = 0.703), and were slaughtered at a BW of 27 kg. Biochemical profiles revealed higher concentrations of ceruloplasmin and low-density lipoproteins, whereas insulin concentration was lower in the RES lambs compared to the ADL group. Liver thiobarbituric acid reactive substances were lower in the RES lambs. No significant differences in ruminal or blood immunological parameters were found. In conclusion, early feed restriction promoted metabolic disorders not related to ruminal acidosis occurrence, which can compromise the health status during the fattening period of merino lambs. |
| first_indexed | 2024-04-11T23:21:34Z |
| format | Article |
| id | doaj.art-fd5eff74d89244d19c7d51d164343705 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-04-11T23:21:34Z |
| publishDate | 2018-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-fd5eff74d89244d19c7d51d1643437052022-12-22T03:57:26ZengMDPI AGAnimals2076-26152018-05-01868310.3390/ani8060083ani8060083Early Feed Restriction Programs Metabolic Disorders in Fattening Merino LambsJavier Frutos0Sonia Andrés1Erminio Trevisi2David R. Yáñez-Ruiz3Secundino López4Alba Santos5F. Javier Giráldez6Instituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas s/n, 24346 Grulleros, León, SpainInstituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas s/n, 24346 Grulleros, León, SpainFaculty of Agriculture, Food and Environmental Science, Institute of Zootechnics, Università Cattolica del Sacro Cuore, Via Emilia Parmense 84, 29122 Piacenza, ItalyEstación Experimental del Zaidín, CSIC, Profesor Albareda 1, 18008 Granada, SpainInstituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas s/n, 24346 Grulleros, León, SpainInstituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas s/n, 24346 Grulleros, León, SpainInstituto de Ganadería de Montaña, CSIC-Universidad de León, Finca Marzanas s/n, 24346 Grulleros, León, SpainEarly postnatal nutrition may have a significant subsequent impact on metabolic disorders during the entire lifespan of lambs. The aim of the present study was to describe the changes in biochemical, immunological, hepatic, and ruminal parameters of fattening lambs derived from early feed restriction during the suckling phase. Twenty-four merino lambs (average body weight, BW, 4.81 ± 0.256 kg) were used, 12 of them were milk-fed ad libitum (ADL) remaining permanently with their dams, whereas the other 12 lambs (restricted, RES) were subjected to milk restriction. After weaning, all the lambs were fed 35 g/kg BW per day of the same complete pelleted diet to ensure no differences between groups in dry matter intake (603 vs. 607 g/day for ADL and RES lambs, respectively, p = 0.703), and were slaughtered at a BW of 27 kg. Biochemical profiles revealed higher concentrations of ceruloplasmin and low-density lipoproteins, whereas insulin concentration was lower in the RES lambs compared to the ADL group. Liver thiobarbituric acid reactive substances were lower in the RES lambs. No significant differences in ruminal or blood immunological parameters were found. In conclusion, early feed restriction promoted metabolic disorders not related to ruminal acidosis occurrence, which can compromise the health status during the fattening period of merino lambs.http://www.mdpi.com/2076-2615/8/6/83metabolic syndromenutritional programminginflammationruminal acidosisfeed efficiencymicrobiota |
| spellingShingle | Javier Frutos Sonia Andrés Erminio Trevisi David R. Yáñez-Ruiz Secundino López Alba Santos F. Javier Giráldez Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs Animals metabolic syndrome nutritional programming inflammation ruminal acidosis feed efficiency microbiota |
| title | Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs |
| title_full | Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs |
| title_fullStr | Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs |
| title_full_unstemmed | Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs |
| title_short | Early Feed Restriction Programs Metabolic Disorders in Fattening Merino Lambs |
| title_sort | early feed restriction programs metabolic disorders in fattening merino lambs |
| topic | metabolic syndrome nutritional programming inflammation ruminal acidosis feed efficiency microbiota |
| url | http://www.mdpi.com/2076-2615/8/6/83 |
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