Ablation in Pancreatic Cancer: Past, Present and Future

The insidious onset and aggressive nature of pancreatic cancer contributes to the poor treatment response and high mortality of this devastating disease. While surgery, chemotherapy and radiation have contributed to improvements in overall survival, roughly 90% of those afflicted by this disease wil...

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Main Authors: Govindarajan Narayanan, Dania Daye, Nicole M. Wilson, Raihan Noman, Ashwin M. Mahendra, Mehul H. Doshi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/11/2511
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author Govindarajan Narayanan
Dania Daye
Nicole M. Wilson
Raihan Noman
Ashwin M. Mahendra
Mehul H. Doshi
author_facet Govindarajan Narayanan
Dania Daye
Nicole M. Wilson
Raihan Noman
Ashwin M. Mahendra
Mehul H. Doshi
author_sort Govindarajan Narayanan
collection DOAJ
description The insidious onset and aggressive nature of pancreatic cancer contributes to the poor treatment response and high mortality of this devastating disease. While surgery, chemotherapy and radiation have contributed to improvements in overall survival, roughly 90% of those afflicted by this disease will die within 5 years of diagnosis. The developed ablative locoregional treatment modalities have demonstrated promise in terms of overall survival and quality of life. In this review, we discuss some of the recent studies demonstrating the safety and efficacy of ablative treatments in patients with locally advanced pancreatic cancer.
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spelling doaj.art-fd616bc3f01a4abf87fc8920e017ec7f2023-11-21T20:41:29ZengMDPI AGCancers2072-66942021-05-011311251110.3390/cancers13112511Ablation in Pancreatic Cancer: Past, Present and FutureGovindarajan Narayanan0Dania Daye1Nicole M. Wilson2Raihan Noman3Ashwin M. Mahendra4Mehul H. Doshi5Miami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USADivision of Vascular and Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Harvard University, Boston, MA 02114, USAHerbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USAHerbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USAPratt School of Engineering, Duke University, Durham, NC 27708, USADepartment of Radiology, Cleveland Clinic Florida, Weston, FL 33331, USAThe insidious onset and aggressive nature of pancreatic cancer contributes to the poor treatment response and high mortality of this devastating disease. While surgery, chemotherapy and radiation have contributed to improvements in overall survival, roughly 90% of those afflicted by this disease will die within 5 years of diagnosis. The developed ablative locoregional treatment modalities have demonstrated promise in terms of overall survival and quality of life. In this review, we discuss some of the recent studies demonstrating the safety and efficacy of ablative treatments in patients with locally advanced pancreatic cancer.https://www.mdpi.com/2072-6694/13/11/2511pancreatic cancerinterventionaloncologyablationIREmicrowave
spellingShingle Govindarajan Narayanan
Dania Daye
Nicole M. Wilson
Raihan Noman
Ashwin M. Mahendra
Mehul H. Doshi
Ablation in Pancreatic Cancer: Past, Present and Future
Cancers
pancreatic cancer
interventional
oncology
ablation
IRE
microwave
title Ablation in Pancreatic Cancer: Past, Present and Future
title_full Ablation in Pancreatic Cancer: Past, Present and Future
title_fullStr Ablation in Pancreatic Cancer: Past, Present and Future
title_full_unstemmed Ablation in Pancreatic Cancer: Past, Present and Future
title_short Ablation in Pancreatic Cancer: Past, Present and Future
title_sort ablation in pancreatic cancer past present and future
topic pancreatic cancer
interventional
oncology
ablation
IRE
microwave
url https://www.mdpi.com/2072-6694/13/11/2511
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AT nicolemwilson ablationinpancreaticcancerpastpresentandfuture
AT raihannoman ablationinpancreaticcancerpastpresentandfuture
AT ashwinmmahendra ablationinpancreaticcancerpastpresentandfuture
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