Glial activation and inflammation along the Alzheimer’s disease continuum

Glial activation and inflammation along the Alzheimer’s disease continuum

Abstract Background Neuronal and glial cell interaction is essential for synaptic homeostasis and may be affected in Alzheimer’s disease (AD). We measured cerebrospinal fluid (CSF) neuronal and glia markers along the AD continuum, to reveal putative protective or harmful stage-dependent patterns of...

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Bibliographic Details
Main Authors: Kaja Nordengen, Bjørn-Eivind Kirsebom, Kristi Henjum, Per Selnes, Berglind Gísladóttir, Marianne Wettergreen, Silje Bøen Torsetnes, Gøril Rolfseng Grøntvedt, Knut K. Waterloo, Dag Aarsland, Lars N. G. Nilsson, Tormod Fladby
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Neuroinflammation
Subjects:
Early diagnosis
Cerebrospinal fluid
ELISA
sTREM2
YKL-40
Chitinase-3-like protein 1
Online Access:http://link.springer.com/article/10.1186/s12974-019-1399-2

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