Different Sensitivity of Control and MICU1- and MICU2-Ablated <i>Trypanosoma cruzi</i> Mitochondrial Calcium Uniporter Complex to Ruthenium-Based Inhibitors

The mitochondrial Ca<sup>2+</sup> uptake in trypanosomatids shares biochemical characteristics with that of animals. However, the composition of the mitochondrial Ca<sup>2+</sup> uniporter complex (MCUC) in these parasites is quite peculiar, suggesting lineage-specific adapta...

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Bibliographic Details
Main Authors: Mayara S. Bertolini, Roberto Docampo
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/23/9316